[Still's syndrome in adults as one of the causes of fever of unknown origin]. / Sindrom Stilla u vzroslykh kak odna iz prichin likhoradki neiasnogo geneza.

Based on their own investigations and reported data, the authors describe the clinical and laboratory signs of Still's syndrome in adults. Special attention is paid to an analysis of the feverish syndrome. The clinical cases of Still's syndrome running its course under the mask of fever of obscure genesis for a long time are provided. The possibilities of early diagnosis of the disease are under discussion.

[The possibilities of an individual approach to intra-articular drug administration in rheumatoid arthritis patients]. / Vozmozhnosti individual'nogo podkhoda k vnutrisustavnomu vvedeniiu medikamentov bol'nym revmatoidnym artritom.

A study was made of the possibilities of an individual approach to intraarticular administration of protease inhibitors, cytostatics and orgoteine in patients with rheumatoid arthritis (RA). The activity of hyaluronidase, superoxide dismutase, the level of rheumatoid factor and the phagocyte count in synovial fluid were examined. With regard to the results of synovial fluid analysis in 67 RA patients, contrykal, orgoteine or cyclophosphamide were administered intra-articularly (based on an individual approach) in addition to corticosteroid hormones. It has been shown that with the individual approach to intraarticular drug administration the number of repeated punctures of the joints decreased by 18.8% while the amount of glucocorticosteroid hormones administered was twice as reduced.

[The status of the pituitary-gonadal system and immunologic parameters in patients with rheumatoid arthritis]. / Sostoianie sistemy gipofiz-gonady i immunologicheskie pokazateli u bol'nykh revmatoidnym artritom.

Male and female patients suffering from rheumatoid arthritis demonstrated disorders in the pituitary-gonadal system, which manifested in the body estrogenization in the presence of androgenic deficiency. The correlations between the levels of estradiol, testosterone and the parameters of the cellular and humoral immunity were analyzed. The authors discuss the problem of the participation of the disorders in the pituitary-gonadal system in the development of an autoimmune process underlying rheumatoid arthritis.