[Clinical manifestations and vascular reactivity in patients with dyscirculatory encephalopathy]. / Klinicheskie proiavleniia i sosudistaia reaktivnost' u bol'nykh distsirkuliatornoi éntsefalopatiei.

Using a neurological, psychiatric, experimental neuropsychological and REG study with the use of functional tests, the authors studied 66 patients with different stages of dyscirculatory encephalopathy and 20 normals of the same age (a control group). These patients demonstrated different degrees of disturbed intellectual and mnestic activities, a drop of attention and general activity, the speed of reactions, as well as different forms of expressed psychoorganic symptoms developing on the background of diffuse and eventually of microfocal neurological symptomatology. The REG data revealed relation between the stage of the disease on the one hand and the state of the vascular tone, elasticity of the vascular wall, level of arterial pessure and pulse blood repletion, the state of the venous outflow on the other. Changes of such parameters indicate to a prevalently functional character of these changes in the I stage and partly in the II stages of dyscirculatory encephalopathy and mainly organic in its III stage.

[Serum antibodies to cytoplasmic antigens of the human brain in patients with multiple sclerosis and amyotropic lateral sclerosis]. / Syvorotochnye antitela k tsitoplazmaticheskim antigenam mozga cheloveka u bol'nykh rasseiannym sklerozom i bokovym amiotroficheskim sklerozom

In order to eliminate antibodies to water soluble proteins of the human brain which were preliminary divided into 10 fractions of DEAE-cellulose, the authors studied the serum of 30 patients with disseminated sclerosis and 30 patients with lateral amyotrophical sclerosis and determined their antithymic serum activity. The antibides were detected only to protein fractions 1,2 and 10. There was a tendency towards a more frequent detection of antibodies with an increase of the severity of the disease. It was not possible to determine antibodies with an increase of the severity of the disease. It was not possible to determine any correlation between the amount of antibodies and such clinical indices as the degree of severity, duration, form of the disorder, age and sex of the patients. The cytotoxic index of the patients was significantly higher than that in normals. The authors also found a correlation between the antibodies in the serum cytoplasmatic brain proteins and antithymic activity of the same sera.