[The syndrome of reduced colonization of periodontium tissues during long-term anti-orthostatic hypokinesia]. / Sindrom snizheniia kolonizatsionnoi rezistentnosti tkanei parodonta v usloviiakh prodolzhitel'noi antiortostaticheskoi gipokinezii.

Effects of antiorthostatic hypokinesia (AOH, -6 degrees) during 60 and 120 days on the parodontium in 10 human subjects aged 24-33 yr. have been studied. Clinical, functional, immunologic, and microbiological analyses were performed 30 days prior to, on days 7 and 30, and on day 7 since the experiment. The parodontium was assessed by relevant indices, immunoglobulines in the oral fluid, and bacteriological parameters determined with the anaerobic cultivation technique. AOH was found to reduce the colonisation resistance of the parodontium due to obviously, the immunologic inertia and consequent changes in the qualitative composition of microflora. It is concluded that the parodontium responds to extreme conditions by replacement of the commensal microflora by opportunistic and obligate parodontosis pathogens.