Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 1 de 1
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Hum Exp Toxicol ; 37(2): 175-184, 2018 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-29320941

RESUMO

The most common delayed complication of sulfur mustard (SM) poisoning has been observed in the respiratory tracts. It was thus aimed to investigate the delayed respiratory complications in SM-exposed patients around 25 years before the study. Forty-three veterans with more than 25% disability of due to SM poisoning were investigated. Clinical examinations as well as pulmonary function test (PFT) were performed. High-resolution computed tomography (HRCT) of the lungs was done as clinically indicated. Triad of chronic cough, dyspnea, and expectoration were the most common symptoms that were recorded in 88.2%, 88.2%, and 64.7% of the patients, respectively. PFT abnormalities were detected in 44.18% of the patients. Restrictive pattern was the most common (41.86%), while pure obstructive pattern did not detect at all. Mixed pattern was significantly correlated with higher disability percentages among the veterans ( p < 0.001). Significant reverse correlation between the disability percentages and forced expiratory volume in 1 s/forced vital capacity ratio was obtained ( p = 0.010, r = -0.389). Air trapping was the most common abnormality in HRCTs (50%). Bronchiectasis (25%), pulmonary fibrosis (25%), and ground-glass attenuation (16.66%) were other common HRCT findings. Comparing with the previous studies on these patients, more restrictive and mixed pattern were observed. Moreover, bronchiolitis, bronchiectasis, and lung fibrosis were the main pathological findings in these patients.


Assuntos
Bronquiectasia/induzido quimicamente , Bronquiolite/induzido quimicamente , Substâncias para a Guerra Química/intoxicação , Exposição por Inalação/efeitos adversos , Pulmão/efeitos dos fármacos , Gás de Mostarda/intoxicação , Fibrose Pulmonar/induzido quimicamente , Saúde dos Veteranos , Adolescente , Adulto , Bronquiectasia/diagnóstico , Bronquiectasia/fisiopatologia , Bronquiolite/diagnóstico , Bronquiolite/fisiopatologia , Tosse/induzido quimicamente , Tosse/fisiopatologia , Estudos Transversais , Avaliação da Deficiência , Dispneia/induzido quimicamente , Dispneia/fisiopatologia , Volume Expiratório Forçado , Humanos , Irã (Geográfico) , Pulmão/diagnóstico por imagem , Pulmão/fisiopatologia , Masculino , Pessoa de Meia-Idade , Fibrose Pulmonar/diagnóstico , Fibrose Pulmonar/fisiopatologia , Fatores de Risco , Espirometria , Fatores de Tempo , Tomografia Computadorizada por Raios X , Capacidade Vital , Adulto Jovem
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...