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1.
J Nucl Med ; 17(4): 268-71, 1976 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-1255251

RESUMO

The roles of 131Cs and 67Ga in the evaluation of solitary thyroid nodules were investigated. Radionuclide scans were performed with 67Ga and 131I in 27 patients and with 131Cs and 131I in 43 patients. Gallium-67 detected only two of eight malignant nonfunctioning nodules and 131Cs detected one of three such nodules. The contribution of 131Cs and 67Ga to the preoperative identification of malignant thyroid lesions is of doubtful value.


Assuntos
Radioisótopos de Césio , Cintilografia , Neoplasias da Glândula Tireoide/diagnóstico , Adenocarcinoma/diagnóstico , Adenoma/diagnóstico , Humanos , Radioisótopos do Iodo
2.
Nucl Med (Stuttg) ; 14(3): 219-27, 1975 Aug 31.
Artigo em Inglês | MEDLINE | ID: mdl-1208204

RESUMO

In 68 euthyroid patients undergoing 131I thyroid function tests the thyroidal, urinary and plasma protein-bound radioactivity has been serially measured for 14 days. The patients were subdivided in controls and 9 groups treated with potassium iodide, carbimazole, potassium perchlorate and TSH, singly or in combination. The aim was to devise a treatment scheme for accelerating the release of iodine from the thyroid and the elimination from the body in cases of accidental radioiodine poisoning if the patient is seen after the radioiodine has already been taken up by the gland. All treatment schedules were effective, but TSH injections gave the best results, especially if combined with carbimazole and potassium perchlorate. This combination is the treatment of choice under these circumstances.


Assuntos
Carbimazol/uso terapêutico , Descontaminação , Radioisótopos do Iodo , Iodeto de Potássio/uso terapêutico , Glândula Tireoide/metabolismo , Tireotropina/uso terapêutico , Proteínas Sanguíneas/metabolismo , Carga Corporal (Radioterapia) , Meia-Vida , Humanos , Iodo/sangue , Iodo/metabolismo , Radioisótopos do Iodo/urina , Ligação Proteica , Glândula Tireoide/efeitos dos fármacos
9.
Gut ; 14(8): 653-6, 1973 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-4743495

RESUMO

Calcium absorption, as measured by whole-body retention of isotopic (47)calcium, was investigated in 10 controls and 10 patients with primary biliary cirrhosis before and after medium-chain triglyceride therapy. Absorption of calcium was impaired in eight patients with primary biliary cirrhosis, three of whom had normal serum bilirubin. Mean absorption was significantly less in patients with primary biliary cirrhosis than in controls. Impaired calcium absorption correlated well with increased faecal fat excretion and less well with the intensity of jaundice. Osteoporosis was diagnosed radiologically in seven patients with primary biliary cirrhosis, and calcium absorption was restored to normal in seven out of eight patients after medium-chain triglyceride therapy. Decrease of steatorrhoea, weight gain, and relief of bone pain have been noted in most patients with primary biliary cirrhosis after therapy. It is concluded that bone disease occurs early in primary biliary cirrhosis, and early medium-chain triglyceride therapy in these patients is suggested.


Assuntos
Cálcio/metabolismo , Absorção Intestinal , Cirrose Hepática Biliar/metabolismo , Triglicerídeos/uso terapêutico , Fosfatase Alcalina/sangue , Bilirrubina , Radioisótopos de Cálcio , Feminino , Humanos , Cirrose Hepática Biliar/terapia , Pessoa de Meia-Idade , Fosfatos/sangue
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