RESUMO
BACKGROUND: This study was performed to assess radiotherapy education among family physicians. METHODS: A questionnaire evaluating radiotherapy training and knowledge was given to participants of a palliative care conference. RESULTS: Thirty-four physicians completed the survey (71% response rate). Major deficiencies in radiotherapy education were identified and 88% of respondents stated that they did not have adequate knowledge. Only 33% had received formal training in radiotherapy and the majority (77%) thought that they would benefit considerably from continuing medical education. CONCLUSIONS: Better education about radiotherapy is required for family physicians and could lead to increased patient referral for such treatment.
Assuntos
Internato e Residência , Médicos de Família/educação , Radioterapia , Adulto , Educação Médica Continuada/organização & administração , Avaliação Educacional/estatística & dados numéricos , Feminino , Humanos , Masculino , Ontário , Inquéritos e QuestionáriosAssuntos
Anticorpos/análise , Antígenos de Plaquetas Humanas , Antígenos HLA/imunologia , Doenças do Sistema Imunitário/etiologia , Doenças do Recém-Nascido/etiologia , Trombocitopenia/etiologia , Adulto , Soro Antilinfocitário/análise , Antígenos de Grupos Sanguíneos , Pai , Feminino , Imunofluorescência , Antígenos HLA/classificação , Humanos , Recém-Nascido , Integrina beta3 , Isoantígenos/análise , MãesRESUMO
This study was undertaken to document the incidence of immediate, nonhemolytic transfusion reactions and to identify a technique or set of techniques that would best identify the different causes of these reactions. A variety of tests were employed to detect lymphocyte, granulocyte, platelet and anti-IgA antibodies. During this study 26,318 units of blood components were transfused on 5,030 occasions. 191 immediate, nonhemolytic reactions were experienced giving an incidence per unit of 0.73%. Blood specimens from 101 of these patients were investigated along with serum from 57 patients who showed no reaction to transfusion as controls. We show that standard B cell lymphocytotoxicity testing is the technique with which most antibodies can be detected (64% of reactors positive vs. 30% of controls, p less than 0.001). Additional tests did not significantly increase the level of antibody detection.
Assuntos
Reação Transfusional , Anticorpos Anti-Idiotípicos/isolamento & purificação , Plaquetas/imunologia , Testes Imunológicos de Citotoxicidade , Feminino , Granulócitos/imunologia , Antígenos HLA/imunologia , Humanos , Imunoglobulina A/imunologia , Isoanticorpos/isolamento & purificação , Linfócitos/imunologia , MasculinoRESUMO
Two cases of neonatal alloimmune thrombocytopenia are presented. Using the indirect immunofluorescence test on platelets in suspension, the presence of non-agglutinating platelet specific antibodies with the specificity anti-Zwa could be demonstrated. In both cases diagnosis of alloimmunization was made before delivery of a second child, typing of the family was done and recommendations could be made concerning clinical management. Compatibility testing between the mother's serum and donor platelets (Zwa-negative) was predictable of a normal transfused platelet survival in the newborn.
