Peristaltic motion of Jeffrey fluid with nonlinear mixed convection.

Since previous few decays the consideration of non-Newtonian liquids motion due to its immense usages in medicine, biology, industrial procedures, chemistry of catalysts and in environment. Various studies examine the significance of bio-materials flow in physiological procedures to explore the cure of diagnosed symptoms of disease appearing during movement in a human physiological system. To illustrate the characteristics of physiological liquids various non-Newtonian models have been proposed, but yet no such single liquid model is exploited which describes all the properties of nonlinear behaving liquids. Among these several non-Newtonian models, Jeffery liquid model should be reduced to its base fluid case (i.e. viscous liquid) by choosing λ1 = λ2 = 0. Various physiological materials which represents both linear and nonlinear characteristics respectively blood is one of these. Jeffery fluid and peristaltic motion have some common properties such as radii, relaxation time and retardation time. Moreover heat and mass transfer is also an important phenomenon which is suitable for various physiological processes such as hemodialysis and oxygenation etc. Thus due to such motivating facts this research is conducted to investigate the peristaltic motion of electrically conducting Jeffery liquid. The peristaltic propagating channel walls are asymmetric and inclined. Joule heating and magnetic field effects are considered by applying magnetic field in transverse direction to the flow. Further conservation laws modelled the flow situation via considering quadric mix convection, thermos diffusion and diffusion-thermos, heat generation and absorption, chemical reaction with activation energy features. Moreover, creeping flow and long wavelength assumptions are used to simplify the mathematical modelling. The reduced system of equation is solved numerically through built-in technique in Mathematica software. This built-in technique is working through ND Solve command and shooting and RK-Felburg numerical schemes are behind this technique. These numerical results are used to discuss the flow quantities i.e., velocity, temperature and concentration against the sundry dimensionless quantities. Examining the results it comes to know that both thermal and concentration nonlinear mix convection have oppositely affecting the axial velocity. Both heat and mass transfer are escalating function of thermo-diffusion/diffusion-thermo aspects.

Numerical analysis of unsteady momentum and heat flow of dusty tangent hyperbolic fluid in three dimensions.

This paper explores the impact of MHD and viscous dissipation with joule heating on convective stretching flow of dusty tangent hyperbolic fluid over a sheet in 3D. A time-dependent magnetic field is applied along the z-axis and the sheet being stretched along the xy-plane. The fluid and dust particles motions are coupled only through drag and heat transfer between them. The effect of viscous dissipation with convection is appreciable when the generated kinetic energy becomes appreciable as compared to the amount of heat transferred. A well known bvp4c method has been used to find the fruitful results. Graphs and tables show the facts and figures for physical properties according to different parameters. The main findings are that Increase in power law index, magnetic field, Weissenberg effect, concentration of dust particles, and unsteadiness parameter reduces the flow of fluid and solid granules.

Numerical analysis of MHD axisymmetric rotating Bodewadt rheology under viscous dissipation and ohmic heating effects.

In present research manuscript, analysis is presented for the influences of heat transition in a bodewadt flow over a penetrable disk numerically. Estimation parameters in current mathematical flow model include magnetic field parameter [Formula: see text] wall suction [Formula: see text] prandtl number [Formula: see text] heat generation/absorption [Formula: see text] eckert number [Formula: see text] variable viscosity [Formula: see text] and thermal conductivity [Formula: see text] The repercussions of joule heating, wall suction, heat generation & absorption, magnetic field, viscous dissipation accompanying with variable characteristics of the fluid are also examined as well. Kinetics of viscous fluid with variable characteristics of fluid having solid body rotation over a permeable disk (having cylindrical geometry) are analyzed. We transformed the governing equations of heat transfer (accompanied by variable properties) and fluid motion in to self-similar non-dimensional differential equations by using the Von-Karman variables which are then further analyzed numerically by utilizing Adams Bashforth method. For a physical insight, results are manifested to scrutinize the behavior of velocity and temperature profiles for different emerging parameters graphically. Moreover, the values of nusselt number & skin friction co-efficient are also computed and physically explicated for the assorted parameters. Outcomes of current investigations are compared with prior work, to ensure the authenticity of the numerical method, and strong agreement is noted.

Analytical investigation of magnetized 2D hybrid nanofluid (GO + ZnO + blood) flow through a perforated capillary.

The hydrothermal features of unsteady, incompressible, and laminar hybrid nanofluid motion through a porous capillary are analytically studied in the magnetic field presence. The hybrid nanofluid (GO + ZnO + Blood) is synthesized by blending nanomaterials of graphene oxide and zinc oxide with blood acting as the host fluid. The mathematical model of the flow comprises of a coupled nonlinear set of partial differential equations (PDEs) satisfying appropriate boundary conditions. These equations are reduced to ordinary differential equations (ODEs) by using similarity transformations and then solved with homotopy analysis method (HAM). The impacts of various pertinent physical parameters over the hybrid nanofluid state functions are examined by displaying 2 D graphs. It has been observed that the fluid velocity mitigates with the varying strength of M, A0, N0, and N1. The enhancing buoyancy parameter ϵ augments the fluid velocity. The increasing Prandtl number causes to reduce, while the enhancing A0, B, and N2 augment the hybrid nanofluid temperature. The fluid concentration mitigates with the higher Schmidt number values and A0, and augments with the increasing Soret number strength. The augmenting magnetic field strength causes to enhance the fluid friction, whereas the convective heat transfer increases with the Prandtl number rising values. The rising Sherwood number drops the mass transfer rate of the fluid. The achieved results are validated due to the agreement with the published results. The results of this computation will find applications in biomedicine, nanotechnology, and fluid dynamics.

A review of COVID-19: Treatment strategies and CRISPR/Cas9 gene editing technology approaches to the coronavirus disease.

The new coronavirus SARS-CoV-2 pandemic has put the world on lockdown for the first time in decades. This has wreaked havoc on the global economy, put additional burden on local and global public health resources, and, most importantly, jeopardised human health. CRISPR stands for Clustered Regularly Interspaced Short Palindromic Repeats, and the CRISPR associated (Cas) protein (CRISPR/Cas) was identified to have structures in E. coli. The most modern of these systems is CRISPR/Cas. Editing the genomes of plants and animals took several years and cost hundreds of thousands of dollars until the CRISPR approach was discovered in 2012. As a result, CRISPR/Cas has piqued the scientific community's attention, particularly for disease diagnosis and treatment, because it is faster, less expensive, and more precise than previous genome editing technologies. Data from gene mutations in specific patients gathered using CRISPR/Cas can aid in the identification of the best treatment strategy for each patient, as well as other research domains such as coronavirus replication in cell culture, such as SARS-CoV2. The implications of the most prevalent driver mutations, on the other hand, are often unknown, making treatment interpretation difficult. For detecting a wide range of target genes, the CRISPR/Cas categories provide highly sensitive and selective tools. Genome-wide association studies are a relatively new strategy to discovering genes involved in human disease when it comes to the next steps in genomic research. Furthermore, CRISPR/Cas provides a method for modifying non-coding portions of the genome, which will help advance whole genome libraries by speeding up the analysis of these poorly defined parts of the genome.

On hybrid nanofluid Yamada-Ota and Xue flow models in a rotating channel with modified Fourier law.

The present study analyzes the comparison of the Xue and Yamada-Ota models for a hybrid nanoliquid flow in porous media occurring amidst a rotating channel with surface catalyzed reaction. Here, the hybrid nanofluid flow is studied under the effect of Cattaneo Christov (C-C) heat flux and homogenous heterogeneous (Homo-Hetero) chemical reaction with entropy generation minimization analysis. The assumptions of the viscosity of hybrid nanomaterial fluid and variable thermal conductivity are added characteristics to the inimitability of the flow model. Two kinds of nanoparticles, namely single-wall carbon nanotubes and multi-wall carbon nanotubes with ethylene glycol (EG) as the base fluid are considered. Carbon nanotubes possess diverse applications in daily life including energy storage, drug delivery, cancer treatment, tissue generation, platelet activation, magnetic force microscopy, and microwave absorption, etc. Similarity transformations are utilized to translate the modeled problem into the coupled ordinary differential equations. This system of ordinary differential equations is addressed numerically. The graphical outcomes are scrutinized by utilizing the MATLAB software bvp4c function. The results revealed that the velocity profile decreases for the higher rotation parameter while increases for the escalated slip parameter. Furthermore, the fluid concentration and temperature are on the decline for higher surface catalyzed reaction and thermal relaxation parameters respectively.

Role of Cattaneo-Christov heat flux in an MHD Micropolar dusty nanofluid flow with zero mass flux condition.

This investigation aims to look at the thermal conductivity of dusty Micropolar nanoliquid with MHD and Cattaneo-Christov heat flux flow over an elongated sheet. The novelty of the envisioned mathematical model is augmented with the added impacts of the heat source/sink, chemical reaction with slip, convective heat, and zero mass flux boundary conditions. The salient feature of the existing problem is to discuss the whole scenario with liquid and dust phases. The graphical depiction is attained for arising pertinent parameters by using bvp4c a built-in MATLAB function. It is noticed that the thermal profile and velocity field increases for greater values of liquid particle interaction parameter in the case of the dust phase. An escalation in the thermal profile of both liquid and dust phases is noticed for the magnetic parameter. The rate of mass transfer amplifies for large estimates of the Schmidt number. The thickness of the boundary layer and the fluid velocity are decreased as the velocity slip parameter is augmented. In both dust and liquid phases, the thermal boundary layer thickness is lessened for growing estimates of thermal relaxation time. The attained results are verified when compared with a published result.

Chemical reaction and thermal radiation impact on a nanofluid flow in a rotating channel with Hall current.

The objective of the present exploration is to examine the nanoliquid flow amid two horizontal infinite plates. The lower plate is stretchable and permeable. The uniqueness of the flow model is assimilated with the Hall effect, variable thermal conductivity, thermal radiation, and irregular heat source/sink. Transmission of mass is enhanced with the impression of chemical reaction incorporated with activation energy. Appropriate similarity transformation is applied to transform the formulated problem into ordinary differential equations (ODEs). The numerical solution is obtained by employing MATLAB software function bvp4c. The dimensionless parameters are graphically illustrated and discussed for the involved profiles. An increasing behavior is exhibited by the temperature field on escalating the Brownian motion, thermophoresis parameter, variable thermal conductivity, and radiation parameter. For larger values of Schmidt number and chemical reaction parameter, the concentration profile deteriorates, while a reverse trend is seen for activation energy. The rate of heat transfer is strengthened at the lower wall on amplifying the Prandtl number. A comparative analysis of the present investigation with already published work is also added to substantiate the envisioned problem.

Impact of autocatalytic chemical reaction in an Ostwald-de-Waele nanofluid flow past a rotating disk with heterogeneous catalysis.

The nanofluids owing to their alluring attributes like enhanced thermal conductivity and better heat transfer characteristics have a vast variety of applications ranging from space technology to nuclear reactors etc. The present study highlights the Ostwald-de-Waele nanofluid flow past a rotating disk of variable thickness in a porous medium with a melting heat transfer phenomenon. The surface catalyzed reaction is added to the homogeneous-heterogeneous reaction that triggers the rate of the chemical reaction. The added feature of the variable thermal conductivity and the viscosity instead of their constant values also boosts the novelty of the undertaken problem. The modeled problem is erected in the form of a system of partial differential equations. Engaging similarity transformation, the set of ordinary differential equations are obtained. The coupled equations are numerically solved by using the bvp4c built-in MATLAB function. The drag coefficient and Nusselt number are plotted for arising parameters. The results revealed that increasing surface catalyzed parameter causes a decline in thermal profile more efficiently. Further, the power-law index is more influential than the variable thickness disk index. The numerical results show that variations in dimensionless thickness coefficient do not make any effect. However, increasing power-law index causing an upsurge in radial, axial, tangential, velocities, and thermal profile.

Determination of in vivo biological activities of Dodonaea viscosa flowers against CCL4 toxicity in albino mice with bioactive compound detection.

Dodonaea viscosa L.Jacq. is an evergreen shrub and native to Asia, Africa, and Australia. It has been used as traditional medicine in different countries. The foremost objective of the current study was to discover the protective potential of D. viscosa flowers Methanol (DVM) and Chloroform (DVC) extracts against CCL4 induced toxicity in mice. This study was intended to identify phytochemicals through HPLC, GCMS, and FT-IR, as well as in vitro antioxidant and in vitro anti-tuberculosis activity. Our comprehensive findings indicate that Dodonaea viscosa is valuable and widespread herbal medicine through therapeutic potentials for curing various ailments. Dodonaeaviscosa flowersare found to have a protective effect against oxidative stress produced by CCL4 in the liver, kidney, and spleen. The intake of DV extracts restored the level of hepatic enzymes (ALP, AST ALT, and Direct bilirubin), hematological parameters (RBCs, WBCs, and Platelets), total protein, and liver antioxidant enzymes (SOD, GPx, and CAT) after a decline in levels by CCL4. Histopathological results discovered the defensive effect of 300 mg/kg of DVM extract against CCL4 induced damage, thus having an improved protective effect compared to DVC and control. As a result of metabolite screening, the total flavonoids and total phenolics were present in abundance. A phytochemical investigation by HPLC identified gallic acid, epicatechin, cumeric acid, flavonoids, while GCMS estimated oleic acid (Octadecenoic acid) (C18H34O2), Stearic acid (C18H36O2), Ricinoleic acid (C18H34O3), and Cedrol (C15H26O). DVM extract exhibited resistance against in vitro Mycobacterium tuberculosis strains. So this study proposed that the protective effect of DV against oxidative damage induced in the liver, kidney, and spleen can be correlated to the antioxidant compounds.

Dispersion of metallic/ceramic matrix nanocomposite material through porous surfaces in magnetized hybrid nanofluids flow with shape and size effects.

Matrix nanocomposites are high performance materials possessing unusual features along with unique design possibilities. Due to extraordinary thermophysical characteristic contained by these matrix nanocomposites materials they are useful in several areas ranging from packaging to biomedical applications. Being an environment friendly, utilization of nanocomposites offer new technological opportunities for several sectors of aerospace, automotive, electronics and biotechnology. In this regards, current pagination is devoted to analyze thermal features of viscous fluid flow between orthogonally rotating disks with inclusion of metallic matrix nanocomposite (MMNC) and ceramic matrix nanocomposites (CMNC) materials. Morphological aspects of these nanomaterials on flow and heat transfer characteristics has been investigated on hybrid viscous fluid flow. Mathematical structuring of problem along with empirical relations for nanocomposites materials are formulated in the form of partial differential equations and later on converted into ordinary differential expressions by using suitable variables. Solution of constructed coupled differential system is found by collaboration of Runge-Kutta and shooting methods. Variation in skin friction coefficient at lower and upper walls of disks along with measurement about heat transfer rate are calculated against governing physical parameters. Impact of flow concerning variables on axial, radial components of velocity and temperature distribution are also evaluated. Contour plots are also drawn to explore heat and thermal profiles. Comparison and critical analysis of MMNc and CMNc have been presented at lower and upper porous disks. Our computed analysis indicates that hybrid nanofluids show significant influence as compared to simple nanofluids with the permutation of the different shape factors.

Nonlinear radiative Maxwell nanofluid flow in a Darcy-Forchheimer permeable media over a stretching cylinder with chemical reaction and bioconvection.

Studies accentuating nanomaterials suspensions and flow traits in the view of their applications are the focus of the present study. Especially, the usage of such materials in biomedical rheological models has achieved great importance. The nanofluids' role is essential in the cooling of small electronic gizmos like microchips and akin devices. Having such exciting and practical applications of nanofluids our goal is to scrutinize the Maxwell MHD nanofluid flow over an extended cylinder with nonlinear thermal radiation amalgamated with chemical reaction in a Darcy-Forchheimer spongy media. The presence of gyrotactic microorganisms is engaged to stabilize the nanoparticles in the fluid. The partial slip condition is considered at the boundary of the stretching cylinder. The Buongiorno nanofluid model is betrothed with impacts of the Brownian motion and thermophoresis. The analysis of entropy generation is also added to the problem. The highly nonlinear system is tackled numerically is addressed by the bvp4c built-in function of the MATLAB procedure. The outcomes of the prominent parameters versus embroiled profiles are portrayed and conversed deeming their physical significance. It is perceived that fluid temperature is augmented for large estimates of the radiation and Darcy parameters. Moreover, it is noticed that the magnetic and wall roughness parameters lower the fluid velocity. To corroborate the presented results, a comparison of the current study with a previously published paper is also executed. An outstanding correlation in this regard is attained.

Theoretical analysis of non-Newtonian blood flow in a microchannel.

BACKGROUND: In this work the theoretical analysis is presented for a electroosmotic flow of Bingham nanofluid induced by applied electrostatic potential. The linearized Poisson-Boltzmann equation is considered in the presence of Electric double layer (EDL). A Bingham fluid model is employed to describe the rheological behavior of the non-Newtonian fluid. Mathematical formulation is presented under the assumption of long wavelength and small Reynolds number. Flow characteristics are investigated by employing Debye-Huckel linearization principle. Such preferences have not been reported previously for non-Newtonian Bingham nanofluid to the best of author's knowledge. METHOD: The transformed equations for electroosmotic flow are solved to seek values for the nanofluid velocity, concentration and temperature along the channel length. RESULTS: The effects of key parameters like Brinkmann number, Prandtl number, Debey Huckel parameter, thermophoresis parameter, Brownian motion parameter are plotted on velocity, temperature and concentration profiles. Graphical results for the flow phenomenon are discussed briefly. CONCLUSIONS: Non-uniformity in channel as well as yield stress τ0 cause velocity declaration for both positive and negative values of U. Nanofluid temperature is found an increasing function of electro osmotic parameter κ if U is positive while it is a decreasing function if U is negative. A completely reverse response is seen in case of concentration profile. The thermophoresis parameter Nt, the Brow nian motion parameter Nb and Brinkman number Br cause an enhancement in temperature. The results are new in case of U.

Inspection of hybrid based nanofluid flow over a curved surface.

BACKGROUND: In this paper, we discussed the Cu - Al2O3/H2O (Hybrid nanofluid) flow over permeable exponentially stretching channel. The hybrid nanofluid involves two kinds of nanoparticles along with base fluid (pure water). Our research objective is to evaluate the heat transfer rate of hybrid nanofluid. METHOD: The resulting system is numerically tackled via shooting method (bvp4c). RESULTS: The hybrid nanofluid gains larger rate of heat transfer as compared to simple nanofluid. The impact of non-dimension parameter on temperature profile, boundary layer will be analyzed for enormous values of dimensionless parameter. Also, boundary layer thickness when γ < 0 (injection) and when γ > 0 (suction) will be compared. The present results with the existence literature will be compared for justification/validation.

Corrigendum to "Transportation of magnetized micropolar hybrid nanomaterial fluid flow over a Riga curface surface" [Comput Meth Prog Bio 185 (2020) 105,136].

This corrigendum corrects the dimensions of partial differential equations in the paper [1], where these mistakes are occurred during typing processes. But the results in [1] does not affect the scientific and mathematical validity of the paper.

Numerical analysis of water based CNTs flow of micropolar fluid through rotating frame.

BACKGROUND: In this article, the nanomaterial flow of micropolar fluid in rotating frame is considered. The SWCNT and MWCNT with base fluid namely pure water is also taken into account to analyze the flow behavior over stretching surface. Mathematical model have been constructed under the nanomaterial of micropolar fluid. METHOD: The governing equations have been developed in the form of system of partial differential equations. The partial differential equations are transformed into ordinary differential equations using similarity transformations. The transformed system has been solved through MAPLE software. RESULTS: The physical parameters like as thermal slip effects, velocity slip effects and magnetic hydrodynamics on the micropolar nanofluid are presented by tables and graphs. Surprisingly in the rotating parameter, F''(0) and - θ'(0) increases for higher values of the rotating parameter while opposite to be noted for G''(0). The Nusselt number and skin friction increases for higher values of micropolar parameter but MWCNT achieves higher heat transfer as associated to SWCNT.

Theoretical investigation of peristaltic activity in MHD based blood flow of non-Newtonian material.

OBJECTIVE: The flow kinetics generated with a pulsatile wave that travel along the channel has prime relevance in various processes in physiology and industry. The aim here is to investigate such phenomenon with Bingham fluid with chemically reacting species in terms of their homogeneous and heterogeneous characteristics. METHOD: To formulate the mathematical descriptions Bingham fluid with heat and mass equations is accounted. Using the similarity solutions, the proposed leading partial differential equations of the flow phenomena transferred into the nonlinear ordinary differential equations and boundary conditions are solved analytically. Such considerations perceive prime importance in medicine and genetics where heterogeneity in a cell makes several diseases difficult to execute. RESULTS: Further the physical aspect of human tabular organs i.e., porosity in a medium is retained in the analysis. The utility of magnetic field in reference to medicine is employed. The walls are considered flexible. The whole problem is set to lubrication approach for simplification of resulting system. The attained results are tested on physical grounds by plotting graphs. CONCLUSION: It is analyzed that the Hartman number and porosity parameter reduce the velocity and temperature profiles. The elastic wall parameters E1 and E2 enhances both the velocity and temperature fields while E3 enrolls an adverse effect.

Transportation of magnetized micropolar hybrid nanomaterial fluid flow over a Riga curface surface.

We deliberated the flow of magnetized micropolar hybrid nanoparticles fluid flow over the Riga curved surface. Exponentially stretching and slip effects are also considered in this analysis. Mathematical model has been established on the base of assumptions in the form of partial differential equations. Such equations are renewed into ordinary differential equations utilizing similarity transformations. Reduced model has been elucidated by means of bvp4c scheme. Impacts of physical parameters namely as stretching parameter R0, curvature parameter K, solid nanoparticle volume fraction Φ2, micropolar parameter K1, microgyration parameter n, thermal slip parameter M, partial slip parameter γ, modified Harman number ∅ and dimensionless parameter ω. Magnetic parameter ß and reciprocal magnetic Prandtl number λ are depicted by means of numerically and graphically. Our results help in the field of engineering and industrial. This model is presented in the first time through literatures. Our interest of study is to be analyzed about the heat transfer rate of magnetized micropolar hybrid nanomaterial fluid over a Riga curved surface. Comparison with the literature has been worked out and excellent agreement is found.

Numerical simulation of electroosmosis regulated peristaltic transport of Bingham nanofluid.

The effects of slip condition and Joule heating on the peristaltic flow of Bingham nanofluid are investigated. The flow is taken in a porous channel with elastic walls. Mathematical formulation is presented under the assumption of long wavelength and small Reynolds number. The transformed equations for the flow are solved to seek values for the nanoparticles velocity, concentration and temperature along the channel length. Graphs are plotted to evaluate the behavior of various physical parameters on flow quantities in both slip and no-slip cases. The main features of the physical parameters are highlighted on the inclined non uniform channel. The results show an increment in velocity with rise in inclination and porosity while it reduces with magnetic field. Moreover, nanofluid favors the heat transfer and decline the concentration.

On both magnetized and non-magnetized dual stratified medium via stream lines topologies: A generalized formulation.

The major concern of current pagination is to report the doubly stratified medium subject to both magnetized and non-magnetized flow fields. For this purpose both the Newtonian and non-Newtonian liquids are considered in a double stratified medium having magnetic field interaction. To be more specific, a generally accepted rheological liquid around a cylindrical surface having constant radius embedded in magnetized doubly stratified media is taken into account. Additionally, flow field is manifested with various pertinent physical effects. The flow problem statement is defended through generalized formulation via fundamental laws. A computational scheme is executed and stream lines topologies are constructed for the both magnetized and non-magnetized stratified medium to explore the interesting features. It is observed that the Casson fluid velocity towards cylindrical surface is higher in magnitude as compared to flat surface. Such observation is same for the both the magnetized and non-magnetized flow fields. Our general formulation yields some existing attempts in the literature. The variations in local skin friction coefficient (LSFC), local Nusselt number (LNN) and local Sherwood number (LSN) are provided with the aid of tabular forms. It is trusted that the obtain observations via stream lines topologies will serve a clear insight to the said flow problem.