1.
Bioorg Med Chem Lett
; 13(15): 2547-51, 2003 Aug 04.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12852963
RESUMO
Coumarin derivatives of different heterocycles (5,7a-i, 10 and 11) were designed based on cyclisation of 2-ethoxy-3-phenylpropanoic acid and 2-benzylmalonic acid as novel lipid-lowering agents and their preliminary in vivo screening indicates 7c has moderate triglyceride-lowering activity.