RESUMO
In the course of research done it was concluded that circulation of pool water through the nuclear reactor core produces a bactericidal effect on microflora due to influence of radiation of various types. Contents of microbes returns to the initial level after 2-4 months after circulation was stopped. Microflora of pool water comprises big amount of coccus, G-positive rods and fungi and a lower content of G-negative rods if compared to water which had been used to fill reactor pool. There is an increased number of radioresistant forms with intensified production of catalase and nuclease. Supposedly, presence of these enzymes gives to the microbes certain advances to survive in high-radiation zones.
Assuntos
Bactérias/isolamento & purificação , Fungos/isolamento & purificação , Reatores Nucleares , Microbiologia da Água , Bactérias/enzimologia , Bactérias/efeitos da radiação , Fungos/efeitos da radiaçãoRESUMO
The combined administration of antibiotic-resistant bifidobacterial strains and the corresponding antibiotics (ampicillin, gentamycin or kanamycin) leads to a greater increase in the survival rate of irradiated mice than the administration of antibiotics only and is a promising method for the treatment of post-irradiation intestinal dysbacteriosis.
Assuntos
Actinomycetaceae/efeitos dos fármacos , Antibacterianos/uso terapêutico , Produtos Biológicos/uso terapêutico , Lesões Experimentais por Radiação/terapia , Ampicilina/administração & dosagem , Animais , Avaliação Pré-Clínica de Medicamentos , Gentamicinas/administração & dosagem , Intestinos/efeitos dos fármacos , Intestinos/microbiologia , Canamicina/administração & dosagem , Camundongos , Resistência às Penicilinas , Lesões Experimentais por Radiação/microbiologia , Lesões Experimentais por Radiação/mortalidade , Fatores de TempoRESUMO
On the basis of an analysis of data from the literature and our own experimental results, the conclusion can be drawn that there is inverse linear dependence between the dose of irradiation and natural resistance of the organism to infection with various infectious agents. With increasing doses of irradiation, the irradiated organism is exposed to greatest risk from the part of the agents of intestinal infections and representatives of normal microflora. These are followed by agents of various diseases of microbial nature. The least decrease can be observed in resistance to viruses.
