Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Quimioterapia do Câncer por Perfusão Regional , Melanoma/tratamento farmacológico , Sarcoma/tratamento farmacológico , Neoplasias Cutâneas/tratamento farmacológico , Adulto , Idoso , Idoso de 80 Anos ou mais , Protocolos de Quimioterapia Combinada Antineoplásica/administração & dosagem , Extremidades , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Fatores de Tempo , Resultado do TratamentoRESUMO
The article is based on an analysis of causes and terms of lethal outcomes of 490 patients after a severe combined trauma. Lethal outcome in 16.9% of the patients took place within an hour after admission to clinic. Within the first 24 hours died 50.2% of the patients, during the second day--8%, on the third day--8.4%. At the period from 3 to 7 days 14.3% of the patients died, during the second week--11.8% of the patients, 7.3% survived for more than 14 days. One direct cause of death was shown in 73.5% of cases, in 21.6%--there were two and in 4.9%--three causes. Acute massive blood loss was the direct cause of death of 43.9% of the patients, critical injury of the brain--in 25.1%, pneumonia--in 27.6%, sepsis--in 6.9%. Altogether 26 causes of lethal outcomes were formulated.