RESUMO
The trauma of the cervical spine was simulated under hexenal anesthesia in non in bred albino rats (100-150 g of weight). The animal was immobilized in a special stand and its head was turned to the right (by 90 degrees) and then tilted back (by 85 degrees). A phase reorganization of the spinal cord architectonics was established in the dynamics of the trauma. In the early period (up to 24 hours), monotypic diminution of the intensity of perfusion of the capillaries with Indian ink was observed with the appearance of no reflow zones, mainly in the regions of "adjacent" blood supply. Later 5-10 days after the trauma, a mosaic pattern of restoration of the perfusion level appeared, which was linked with the different conditions for normalization of the blood flow in some of the spinal cord regions.
Assuntos
Vértebras Cervicais/lesões , Medula Espinal/irrigação sanguínea , Animais , Doença Crônica , Microcirculação/patologia , Ratos , Medula Espinal/patologia , Fatores de TempoAssuntos
Artéria Basilar/fisiopatologia , Vértebras Cervicais/lesões , L-Lactato Desidrogenase/metabolismo , Artéria Vertebral/fisiopatologia , Animais , Encéfalo/enzimologia , Vértebras Cervicais/enzimologia , Isoenzimas , Masculino , Ratos , Fluxo Sanguíneo Regional , Fatores de Tempo , Insuficiência Vertebrobasilar/enzimologia , Insuficiência Vertebrobasilar/etiologiaRESUMO
The author measured the blood content of the vertebrobasilar bed in rats with a cervical trauma induced by backward bending and simultaneous rotation of the neck. The blood content of the vessels was found to undergo a phasic reduction at both the cerebral and spinal levels depending on the duration of the posttraumatic period. It was demonstrated that a neuro-reflectory spasm of the extracranial portion of the vertebral arteries is the cause underlying the development and evolution of the above changes in the circulation system in the given injury.