1.
Cardiology
; 90(1): 43-7, 1998 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-9693170
RESUMO
Lymphocytes can be activated to produce and release opioid peptides. We investigated the levels of immunoreactive beta-endorphin in peripheral blood mononuclear cells from 11 patients with acute myocardial infarction. The concentrations of beta-endorphin in mononuclear leukocytes of 30.2 +/- 6.9 pg/10(6) cells on admission were in the normal range of 20-40 pg/10(6) cells and decreased significantly to 6.9 +/- 1.9 pg/10(6) cells after 48 h (p < 0.05). Decreased levels of mononuclear leukocyte-associated beta-endorphin in acute myocardial infarction may be due to the release of endogenous opioid after stimulation by stress and acute-phase reactants and play a role in inflammation and pain.
Assuntos
Leucócitos Mononucleares/metabolismo , Infarto do Miocárdio/sangue , beta-Endorfina/sangue , Proteína C-Reativa/análise , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , beta-Endorfina/imunologia
2.
Anesth Analg
; 86(3): 670-2, 1998 Mar.
Artigo
em Inglês
| MEDLINE
| ID: mdl-9495436