RESUMO
Multiple subcutaneous masses from two sibling bearded dragons were removed. Nodules were well demarcated, restricted to the subcutis, and soft, white to yellow, resembling adipose tissue. Histologically, the masses were composed of short interlacing streams and bundles of spindle cells, with regions of vague nuclear palisading. Two of the tumors contained a subpopulation of polygonal cells with abundant periodic acid-Schiff (PAS)-positive cytoplasmic granules. Neoplastic cells were immunohistochemically positive for S100 and neuron-specific enolase (NSE) but negative for desmin and smooth muscle actin. Electron microscopy and reticulin stains demonstrated a continuous basal lamina separating intertwining cells. Histologic, ultrastructural, and immunohistochemical features were consistent with a peripheral nerve sheath origin. At 1 year postexcision, local reoccurrence of a single incompletely excised mass from the left shoulder was noted.
Assuntos
Iguanas , Neoplasias de Bainha Neural/patologia , Neoplasias de Bainha Neural/veterinária , Neurilemoma/patologia , Neurilemoma/veterinária , Animais , Imuno-Histoquímica/veterinária , Microscopia Eletrônica de Transmissão/veterinária , Neoplasias de Bainha Neural/cirurgia , Neurilemoma/cirurgia , Fosfopiruvato Hidratase , Proteínas S100 , Coloração e RotulagemRESUMO
An adult male mountain chameleon (Chameleo montium), one of 92 individuals recently caught in the wild and transported, died after a 28-day history of anorexia. Gross examination revealed marked emaciation and enteric nematodiasis. Histopathologic examination of the small intestine revealed moderate numbers of enterocytes containing 2-15 micrometer-diameter round to ellipsoid, basophilic, intranuclear inclusions. Ultrastructurally, the inclusions consisted of crystalline arrays of hexagonal viral particles 67-76 nm in diameter with electron-dense cores. The viral particles were consistent with an adenovirus. No pathologic changes were associated with the adenoviral infection.
