RESUMO
The study covered clinical and laboratory findings, immunity parameters in 103 workers of polymer compounds production. The individuals exposed to chlorine organic chemicals: mercuric vapors, gaseous chlorine demonstrate specific changes of metabolic parameters. The data on protein synthesis, monooxygenases activity, lipid metabolism, state of membranes (lipoprotein complex, peroxidases, ALa-AT, Asp-AT), immune activity enabled to design prophylactic measures. To accomplish the therapeutic measures, the department for prevention of occupational intoxication is organized in local industrial medical center.
Assuntos
Indústria Química , Doenças Profissionais/induzido quimicamente , Cloreto de Polivinila/efeitos adversos , Adulto , Fatores Etários , Ensaios Enzimáticos Clínicos , Feminino , Humanos , Masculino , Doenças Profissionais/diagnóstico , Doenças Profissionais/prevenção & controle , Fatores SexuaisRESUMO
The results of the toxico-hygienic study of 12 types of rosins are presented. It is established that these compounds are moderately hazardous products with slightly pronounced local irritating and skin resorptive effect accompanied by moderate sensitizing activity. Rosins' cumulative characteristics are not manifested at the lethal level. Lim(ac) are within 110-193 mg/m3 and Lim(ch) within 38.0-42.0 mg/m3. The analyzed types of rosins possess polytropic general toxicity with primary impact on the functional state of liver, kidneys and the nervous system. The above studies have enabled one to recommend group MAC for rosins in the workplace air at the level of 4 mg/m3 and their marking as allergens.