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Sci Rep ; 14(1): 14572, 2024 06 24.
Artigo em Inglês | MEDLINE | ID: mdl-38914689

RESUMO

Thyroid eye disease (TED) is a common ophthalmologic manifestation of thyroid dysfunction. Despite various imaging techniques available, there hasn't been a widely adopted method for assessing the anterior segment vasculature in TED patients. Our study aimed to evaluate alterations in ocular surface circulation following orbital decompression surgery in TED patients and investigate factors influencing these changes. Using anterior segment optical coherence tomography-angiography (AS-OCTA), we measured ocular surface vascularity features, including vessel density (VD), vessel diameter index (VDI), and vessel length density (VLD), both before and after decompression surgery, alongside standard ophthalmic examinations. Our AS-OCTA analysis revealed a significant decrease in most of the temporal vasculature measurements six weeks post-surgery (p < 0.05). However, differences in the nasal region were not statistically significant. These findings indicate notable changes in ocular surface circulation following orbital decompression in TED patients, which may have implications for intraocular pressure (IOP) control and ocular surface symptoms management. AS-OCTA holds promise as a tool for evaluating the effectiveness of decompression surgery and assessing the need for further interventions.


Assuntos
Descompressão Cirúrgica , Oftalmopatia de Graves , Tomografia de Coerência Óptica , Humanos , Oftalmopatia de Graves/cirurgia , Oftalmopatia de Graves/diagnóstico por imagem , Tomografia de Coerência Óptica/métodos , Masculino , Feminino , Descompressão Cirúrgica/métodos , Pessoa de Meia-Idade , Adulto , Órbita/irrigação sanguínea , Órbita/diagnóstico por imagem , Órbita/cirurgia , Idoso , Angiografia/métodos
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