Your browser doesn't support javascript.
loading
Mostrar: 20 | 50 | 100
Resultados 1 - 5 de 5
Filtrar
Mais filtros










Base de dados
Intervalo de ano de publicação
1.
Clin Radiol ; 75(6): 441-447, 2020 06.
Artigo em Inglês | MEDLINE | ID: mdl-32061396

RESUMO

AIM: To describe the magnetic resonance imaging (MRI) findings of the cervical spine of patients with mucopolysaccharidosis type VI (MPS VI) and correlate them with clinical manifestations. MATERIALS AND METHODS: This is a cross-sectional study involving 12 patients with MPS VI. A limited neurological examination was undertaken in each patient including Tinel's test, assessment of muscle tone, and the evaluation of deep tendon reflexes. Additionally, each patient underwent cervical spine MRI to evaluate platybasia, odontoid dysplasia, periodontoid soft-tissue thickening, spinal canal stenosis, myelopathy, basilar invagination, platyspondyly, and reduction of nasopharyngeal airway. RESULTS: Nine patients were male (75%). The average age was 12.5 (±3.5 years). Tinel's test was negative in all patients. No muscle tone abnormalities were observed. Approximately 48% of the tested reflexes were considered abnormal, 10 of which (8.3%) were pathological occurring in five different patients (41.6%). At MRI, all patients showed periodontoid soft-tissue thickening and cervical spinal stenosis; six showed spinal cord compression and two showed myelopathy. Odontoid hypoplasia and basilar invagination were observed in nine patients. All patients with cervical stenosis on MRI had abnormal reflexes; however, only two of the six patients with evidence of cord compression on MRI had abnormal reflexes on clinical examination. CONCLUSIONS: The present study of 12 patients with MPS VI demonstrated that a normal neurological examination cannot confidently exclude potential cord compression in patients with this condition. MRI may aid in the timely identification of cervical spine abnormalities, and potentially play a role in lessening morbidity and mortality in patients with MPS.


Assuntos
Vértebras Cervicais/diagnóstico por imagem , Imageamento por Ressonância Magnética/métodos , Mucopolissacaridose VI/diagnóstico por imagem , Compressão da Medula Espinal/diagnóstico por imagem , Criança , Estudos Transversais , Feminino , Humanos , Masculino , Exame Neurológico
2.
Arch Soc Esp Oftalmol ; 92(4): 181-183, 2017 Apr.
Artigo em Inglês, Espanhol | MEDLINE | ID: mdl-27793489

RESUMO

CASE REPORT: A male patient with an exposure keratopathy caused by lagophthalmos. A gold weight was implanted in the right upper eyelid. Eight months later, he presented with erythema and swelling of right upper eyelid. An incisional biopsy was performed, reporting extranodal marginal zone B cell lymphoma. DISCUSSION: when a tumour at the site of a gold weight implant is refractory to treatment, it is essential to perform an incisional biopsy to establish the histopathological diagnosis. Ocular adnexal lymphomas are relatively common. The presence of foreign material can cause chronic inflammation that could be the stimulus for the development of a lymphoproliferative disorder.


Assuntos
Neoplasias Palpebrais/etiologia , Linfoma de Zona Marginal Tipo Células B/etiologia , Complicações Pós-Operatórias/etiologia , Próteses e Implantes/efeitos adversos , Idoso , Doenças Palpebrais/cirurgia , Ouro , Humanos , Masculino
3.
Braz J Biol ; 72(1): 33-9, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22437382

RESUMO

Feeding behavior of the invasive bivalve Limnoperna fortunei in the presence of single-celled, colonial, and filamentous cyanobacteria was tested in laboratory experiments to evaluate the effects of size and shape on mussel feeding. The first hypothesis holds that golden mussel filters more efficiently smaller particles, such as single cells of Microcystis, which could be more easily assimilated by its filtering apparatus. The second hypothesis sustains that L. fortunei filters more efficiently rounded colonies, such as Microcystis, which would be more easily ingested than lengthy filamentous, such as Planktothrix. Filtration rates of golden mussel in the presence of single-celled, colonial and filamentous cyanobacteria were similar. Nevertheless, there was a great difference in the ingestion and pseudofeces production rates. Single cells were widely accepted as food, while filamentous and colonial cyanobacteria were massively expelled as pseudofeces. The results confirmed the first hypothesis that golden mussel prefers to ingest smaller particles. The second hypothesis was rejected since filamentous were preferentially ingested than colonial cyanobacteria. Golden mussel has the potential to remove toxic cells (Microcystis), however this potential would be reduced in cyanobacteria blooms, where colonial forms which are preferentially rejected by L. fortunei, are predominant. In this case, the presence of this invasive bivalve could also enhance the occurrence of blooms by rejecting colonial and filamentous cyanobacteria in pseudofeces.


Assuntos
Bivalves/fisiologia , Cianobactérias , Comportamento Alimentar/fisiologia , Animais , Microcystis , Tamanho da Partícula , Análise de Célula Única
4.
Braz J Biol ; 72(1): 41-9, 2012 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-22437383

RESUMO

The aim of this study was to test the effects of cyanobacteria toxicity on feeding behavior of the golden mussel Limnoperna fortunei. First, it was tested the hypothesis that L. fortunei preferentially graze on non-toxic phytoplankton and reject toxic cyanobacteria. Second, it was tested the hypothesis that toxic cyanobacteria negatively affect feeding and survival of L. fortunei. The present study is the first to evaluate the effects of toxic cyanobacteria on L. fortunei feeding and survival. In the short-term grazing, golden mussel filtration rates were evaluated in the presence of toxic and non-toxic strains of cyanobacteria Microcystis aeruginosa, and non-toxic phytoplankton Nitzschia palea. Highest filtration rates were registered when mussels fed on Nitzschia. Despite that, golden mussel expelled Nitzschia cells in large quantities and preferentially ingested Microcystis cells, both toxic and non-toxic strains. In the long-term grazing, mussels were exposed to toxic and non-toxic strains of Microcystis during 5 days. Filtration rates were not significantly different for toxic and non-toxic Microcystis throughout exposure period. The results have demonstrated cyanobacteria toxicity is not the main factor influencing L. fortunei feeding behavior. Survival of L. fortunei feeding on toxic cyanobacteria shows the potential of this invasive bivalve as a vector to the transference of cyanotoxins to higher trophic levels.


Assuntos
Toxinas Bacterianas/toxicidade , Bivalves/fisiologia , Comportamento Alimentar/fisiologia , Microcystis/química , Animais , Fatores de Tempo
5.
Med Cutan Ibero Lat Am ; 5(2): 135-50, 1977.
Artigo em Português | MEDLINE | ID: mdl-345018

RESUMO

The delayed hypersensitivity to antibiotics existing in Brazil, including the systemically administered, is analyzed. The sulphanilamide, penicillin, neomycin, oxacillin, oxitetraciclyne, chloramphenicol and kanamycin were the more positive to the contact test. We do not find any difference in the test between sex and race. The positivity was 7,5 times higher in adults than in children. In spite the high positivity in atopic patients we could not demonstrate the same in patients with other allergic procesus history.


Assuntos
Antibacterianos/efeitos adversos , Hipersensibilidade a Drogas/etiologia , Hipersensibilidade Tardia/etiologia , Brasil , Ensaios Clínicos como Assunto , Avaliação de Medicamentos , Feminino , Humanos , Masculino
SELEÇÃO DE REFERÊNCIAS
DETALHE DA PESQUISA
...