RESUMO
The second reported case of an anterior urethral polyp is presented. The etiology, pathology and treatment of urethral polyps are discussed.
Assuntos
Pólipos , Neoplasias Uretrais , Criança , Humanos , Masculino , Pólipos/diagnóstico por imagem , Pólipos/patologia , Pólipos/cirurgia , Radiografia , Neoplasias Uretrais/diagnóstico por imagem , Neoplasias Uretrais/patologia , Neoplasias Uretrais/cirurgiaRESUMO
Two cases of pancreatic polypeptide cell hyperplasia were obtained by operation. The first case exhibited adenocarcinoma of the stomach with metastases to the neck lymph nodes and pancreatic polypeptide hypersecretion. Pancreatic polypeptide cell hyperplasia was confirmed by the immunoperoxidase method and by the elevated level of pancreatic polypeptide in the pancreatic extracts and in the circulating blood. There was no watery diarrhea syndrome. The second case presented with persistent watery diarrhea of two and one-half year duration, and the resected pancreas contained extremely large atypical islets, exclusively composed of pancreatic polypeptide cells. It is speculated that in some cases pancreatic polypeptide oversecretion may be causative for pseudo-Verner-Morrison syndrome in the absence of ulcer of carcinoma in the upper gastrointestinal tract.
Assuntos
Diarreia/etiologia , Pâncreas/patologia , Polipeptídeo Pancreático/biossíntese , Adenocarcinoma/complicações , Idoso , Feminino , Humanos , Hiperplasia/complicações , Hiperplasia/patologia , Ilhotas Pancreáticas/ultraestrutura , Metástase Linfática , Masculino , Microscopia Eletrônica , Pessoa de Meia-Idade , Pâncreas/metabolismo , Pâncreas/ultraestrutura , Radioimunoensaio , Neoplasias Gástricas/complicaçõesAssuntos
Neoplasias Ósseas , Tumores de Células Gigantes , Tíbia , Adolescente , Neoplasias Ósseas/patologia , Neoplasias Ósseas/cirurgia , Feminino , Tumores de Células Gigantes/patologia , Tumores de Células Gigantes/cirurgia , Humanos , Recidiva Local de Neoplasia , Tíbia/patologia , Tíbia/cirurgiaRESUMO
Studies were made of a well functioning geometric total knee prosthesis, removed at autopsy from a sixty-one-year-old man, which had been used for eight months. The components were firmly embedded in bone with no evidence of loosening. There was significant deformation of the polyethylene tibial component, but no significant wear on the metallic component. Thin layers of fibrous tissue were found in some areas of the bone-cement interfaces.
Assuntos
Prótese Articular , Joelho , Acrilatos/uso terapêutico , Artrite Reumatoide/cirurgia , Artroplastia/métodos , Autopsia , Cimentos Ósseos , Estudos de Avaliação como Assunto , Fêmur/cirurgia , Humanos , Joelho/cirurgia , Masculino , Pessoa de Meia-Idade , Osteotomia/métodos , Polietilenos , Desenho de Prótese , Sinovectomia , Tíbia/patologia , Tíbia/cirurgiaRESUMO
Antibody to a breast cancer antigen was detected by immunodiffusion or complement fixation in at least one serum sample in 46% of 84 patients with a diagnosis of carcinoma, 34% of 96 patients with fibrocystic disease and 25% of 44 patients with fibroadenoma. A single serum sample obtained from screenees of the Detection Center for Breast Diseases was tested by immunodiffusion only and antibody was found in 3 of 206 screenees (1.5%). Eleven of 13 patients with breast cancer metastatic to lymph nodes and no detectable serum antibody either had recurrence or were dead within 12 months of mastectomy. Fifteen of 18 patients with breast cancer metastatic to lymph nodes and with detectable serum antibody were alive and free of disease for up to 24 months. Histologic slides from patients with a diagnosis of fibrocystic disease or fibroadenoma were reviewed for the presence of ductal epithelial hyperplasia. Ductal epithelial hyperplasia was present in a similar per cent of patients with no detectable serum antibody as those with antibody detected in the serum. Severe sinus histiocytosis of the axillary lymph nodes was present in 45% of those cancer patients with serum antibody and only 11% of those cancer patients with no detectable serum antibody.