RESUMO
The present study compares two methods of local application of prostaglandins prior to surgical abortion in the first trimester. Fifty patients were treated with a vaginal tablet of Gemeprost (E1 analogue); 50 others by the intra-cervical application of PGF2 alpha gel. Gemeprost was found to be superior to the PGF2 alpha gel. Several hypotheses are formulated to explain this observation. The side effects of the two methods are compared and discussed.
Assuntos
Aborto Induzido/métodos , Alprostadil/análogos & derivados , Colo do Útero/efeitos dos fármacos , Prostaglandinas F/administração & dosagem , Administração Tópica , Adulto , Alprostadil/administração & dosagem , Alprostadil/efeitos adversos , Dilatação/métodos , Dinoprosta , Feminino , Géis , Humanos , Dor/fisiopatologia , Paridade , Gravidez , Primeiro Trimestre da Gravidez , Estudos Prospectivos , Prostaglandinas F/efeitos adversos , ComprimidosRESUMO
A total of 1552 antepartum nonstress tests performed during the week before delivery are analyzed with respect to both reactivity and the presence of pathologic baseline patterns (tachycardia, bradycardia, diminished beat-to-beat variability) or decelerations. Correlation with mode of delivery and condition of the newborn infant shows that, irrespective of nonstress test reactivity, the presence of baseline anomalies and/or decelerations is associated with significantly increased perinatal morbidity and mortality. Nonstress test analysis, if systematic, that is, not restricted to reactivity alone, makes it possible to better detect fetuses at high perinatal risk, in which case closer surveillance would be indicated.
