[Influence of pancreatic insulin reserve on the metabolic control of type I and II diabetes mellitus]. / Influencia de la reserva pancreática de insulina sobre el control metabólico de las diabetes tipos I y II.

We have studied 22 diabetic patients, 14 type I and 8 type II, in order to determine if there is a correlation between metabolic control and pancreatic reserve of insulin. All the patients were treated with optimum doses of bolus/basal insulin. They underwent a peptide C test (at baseline and after 3 stimulus with glucagon) and every month, during 3 months, HbA1c and fructosamine were measured, with monthly self control of glycemia. Both HbA1c and fructosamine showed a statistically significant improvement during the study. In all the cases, there was a negative correlation between metabolic control and pancreatic reserve, with statistical significance for type I, especially regarding the response of peptide C to the administration of glucagon. We conclude that the preservation of a good endogenous secretion of insulin benefits the metabolic control of diabetes.

Tooth eruption in children with growth deficit.

The authors aim to study the relation existing between the chronology of tooth eruption and delayed growth, whether this is delayed growth with or without low genetic height or delayed growth caused by growth hormone deficit. The 50 children included in the sample were studied from the endocrine and dental points of view and it was found that children whose delayed growth is accompanied by a low genetic height or growth hormone deficit presented retardation in dentition and retardation in bone age. However, a retardation in bone age does not necessarily imply a retardation in dentition.