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1.
Chem Commun (Camb) ; 55(87): 13085-13088, 2019 Oct 29.
Artigo em Inglês | MEDLINE | ID: mdl-31608913

RESUMO

We report the development of a new class of "water-in-salt" electrolytes based on UV photopolymerized acrylic polymers. Incorporation of "water-in-bisalt" in a polymer matrix reduces water activity, expands the electrochemical stability window to 4.1 V, and dramatically improves cycle life in full cells with lithium titanate anodes compared to liquid water-based electrolytes.

2.
J Biomater Appl ; 30(7): 1049-59, 2016 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-26589295

RESUMO

Prompt emergency treatment for ocular injury, particularly in a battlefield setting, is essential to preserve vision, reduce pain, and prevent secondary infection. A bandage contact lens that could be applied in the field, at the time of injury, would protect the injured ocular surface until hospital treatment is available. Cellulose, a natural polymer, is widely used in biomedical applications including bandage materials. Hydrogels synthesized from different cellulose sources, such as plants, cotton, and bacteria, can have the optical transparency and mechanical strength of contact lenses, by tailoring synthesis parameters. Thus, we optimized the fabrication of cellulose-based hydrogels and evaluated their in vivo biocompatibility and related physical properties. Our data demonstrate that along with tailorable physical properties, our novel cellulose-based hydrogels could be made with contact lens geometry, exhibit no significant signs of material toxicity after 22 days of in vivo testing, and show significant promise for use as a corneal bandage immediately following ocular trauma.


Assuntos
Materiais Biocompatíveis/química , Celulose/química , Lesões da Córnea/prevenção & controle , Traumatismos Oculares/terapia , Hidrogéis/química , Animais , Lentes de Contato , Lentes de Contato Hidrofílicas , Córnea/patologia , Feminino , Masculino , Teste de Materiais , Oxigênio/química , Permeabilidade , Polímeros/química , Coelhos , Ratos , Ratos Sprague-Dawley , Silicones/química
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