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1.
J Ark Med Soc ; 106(9): 208-9, 2010 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-20337168

RESUMO

Coronary reoperations continue to play an important role in the practice of coronary artery bypass grafting (CABG). Apart from having a sicker patient subgroup, reoperation poses an increasingly more complex and technically demanding surgery to perform. The superior patency of the left internal mammary artery (LIMA) has prompted increased interest in using arterial conduits for coronary bypass. However in situations where LIMA to left anterior descending (LAD) graft can not be done successfully, it remains a problem. We present a case of repeat three vessel coronary bypass surgery where three free arterial grafts were used with single anastomosis to ascending aorta as an alternative because of compromised length of LIMA and radial grafts.


Assuntos
Anastomose Cirúrgica/métodos , Aorta/cirurgia , Ponte de Artéria Coronária/métodos , Doença da Artéria Coronariana/cirurgia , Angiografia Coronária , Doença da Artéria Coronariana/diagnóstico por imagem , Humanos , Masculino , Pessoa de Meia-Idade , Resultado do Tratamento
2.
N Engl J Med ; 358(25): 2688-97, 2008 Jun 19.
Artigo em Inglês | MEDLINE | ID: mdl-18565861

RESUMO

BACKGROUND: Sudden death can occur as a consequence of cardiac-conduction abnormalities in the neuromuscular disease myotonic dystrophy type 1. The determinants of the risk of sudden death remain imprecise. METHODS: We assessed whether the electrocardiogram (ECG) was useful in predicting sudden death in 406 adult patients with genetically confirmed myotonic dystrophy type 1. A patient was characterized as having a severe abnormality if the ECG had at least one of the following features: rhythm other than sinus, PR interval of 240 msec or more, QRS duration of 120 msec or more, or second-degree or third-degree atrioventricular block. RESULTS: Patients with severe abnormalities according to the entry ECG were older than patients without severe abnormalities, had more severe skeletal-muscle impairment, and were more likely to have heart failure, left ventricular systolic dysfunction, or atrial tachyarrhythmia. Such patients were more likely to receive a pacemaker or an implantable cardioverter-defibrillator during the follow-up period. During a mean follow-up period of 5.7 years, 81 patients died; there were 27 sudden deaths, 32 deaths from progressive neuromuscular respiratory failure, 5 nonsudden deaths from cardiac causes, and 17 deaths from other causes. Among the 17 patients who died suddenly in whom postcollapse rhythm was evaluated, a ventricular tachyarrhythmia was observed in 9. A severe ECG abnormality (relative risk, 3.30; 95% confidence interval [CI], 1.24 to 8.78) and a clinical diagnosis of atrial tachyarrhythmia (relative risk, 5.18; 95% CI, 2.28 to 11.77) were independent risk factors for sudden death. CONCLUSIONS: Patients with adult myotonic dystrophy type 1 are at high risk for arrhythmias and sudden death. A severe abnormality on the ECG and a diagnosis of an atrial tachyarrhythmia predict sudden death. (ClinicalTrials.gov number, NCT00622453.)


Assuntos
Arritmias Cardíacas/diagnóstico , Morte Súbita Cardíaca/etiologia , Eletrocardiografia , Distrofia Miotônica/complicações , Adulto , Arritmias Cardíacas/etiologia , Causas de Morte , Feminino , Seguimentos , Humanos , Masculino , Pessoa de Meia-Idade , Distrofia Miotônica/mortalidade , Prognóstico , Fatores de Risco , Taquicardia/diagnóstico , Taquicardia/etiologia
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