The CANDOR corpus: Insights from a large multimodal dataset of naturalistic conversation.

People spend a substantial portion of their lives engaged in conversation, and yet, our scientific understanding of conversation is still in its infancy. Here, we introduce a large, novel, and multimodal corpus of 1656 conversations recorded in spoken English. This 7+ million word, 850-hour corpus totals more than 1 terabyte of audio, video, and transcripts, with moment-to-moment measures of vocal, facial, and semantic expression, together with an extensive survey of speakers' postconversation reflections. By taking advantage of the considerable scope of the corpus, we explore many examples of how this large-scale public dataset may catalyze future research, particularly across disciplinary boundaries, as scholars from a variety of fields appear increasingly interested in the study of conversation.

Evaluación Comparativa de la Inflamación de Tejidos Blandos en Pacientes Sometidos a Exodoncias de Terceros Molares con y sin Uso de PRF

RESUMEN: La exodoncia de los terceros molares, es uno de los procedimientos ambulatorios más frecuente en la cirugía oral, donde habitualmente requiere de osteotomías y odontosección. Es por el cual, el manejo de la inflamación postoperatoria ha ido variando, con el fin de obtener mejores resultados con el menor riesgo posible. Comparar la eficacia de Dexametasona versus L- PRF en el control de la inflamación, dolor y trismus, en pacientes sin patologías basales sometidos a exodoncias de terceros molares inferiores incluidos y semi incluidos. Se realizó un estudio experimental clínico controlado aleatorizado, autorizado por el comité de ética de la Universidad Andrés Bello, con el código PROPRGFO 54- 2019. El tamaño muestral fue de 31 pacientes, dividido en 2 grupos, Grupo A Dexametasona (15) y Grupo B PRF (16). Ambos grupos fueron medicados de manera IV con Cefazolina 1 gr y Ketoprofeno 100 mg. Excepcionalmente al grupo A se le administró Dexametasona 4 mg. Una vez realizada la extracción del tercer molar, se aplicó L-PRF en el alvéolo de los pacientes del grupo B. Se indicaron los mismos cuidados y medicación postquirúrgica para ambos grupos. Cada paciente se controló en 4 ocasiones: Antes de la cirugía, inmediatamente después, a las 72 horas y a los 7 días de realizada la intervención, donde se consignaron las medidas faciales según el método de Neupert. Además, se registró la intensidad de dolor según escala EVA y longitud de apertura bucal. No existen diferencias estadísticamente significativas en cuanto a inflamación entre ambos grupos analizados, ni en cuanto al control de la inflamación entre cada instante de tiempo, cuando se analizó cada método por separado. Se puede considerar al L-PRF como una alternativa a la medicación preoperatoria clásica para disminuir la inflamación y complicaciones postoperatorias en pacientes en los cuales está contraindicado el uso de corticoides.

ABSTRACT: Third molar extraction is one of the most frequent outpatient procedures in oral surgery, usually requiring osteotomies and odontosection. For this reason, the management of post operative inflammation has been varying in order to obtain better results with the lowest posible risk. The aim was to compare the efficacy of Dexamethasone versus L-PRF in the control of inflammation, pain and trismus in patients without basal pathologies who underwent exodontia of included and semi-included lower third molars. A randomised controlled clinical experimental study was carried out, authorised by the ethics committee of the Universidad Andrés Bello, with code PROPRGFO 54- 2019. The simple size was 31 patients, divided into 2 groups, Group A Dexamethasone (15) and Group B PRF (16). Both groups were medicated IV with Cefazolin 1 g and Ketoprofen 100 mg. Exceptionally, group A was given Dexamethasone 4 mg. After the extraction of the third molar, L-PRF was applied to the alveolus of group B patients. The same post- surgical care and medication was indicated for both groups. Each patient was monitored on 4 occasions: Before surgery, immediately after, 72 hours and 7 days after surgery, where facial measurements were recorded according to Neupert's method. In addition, pain intensity was recorded according to the VAS scale and buccal opening length. There are no statistically significant differences in terms of inflammation between the two groups analysed, nor in L-PRF can be considered as an alternative to classic preoperative medication to reduce inflammation and post operative complications in patients in who use of corticosteroids is contraindicated.

Exploring public sentiment on enforced remote work during COVID-19.

Due to the coronavirus disease 2019 (COVID-19) pandemic, many employees have been strongly encouraged or mandated to work from home. The present study sought to understand the attitudes and experiences of the general public toward remote work by analyzing Twitter data from March 30 to July 5 of 2020. We web scraped over 1 million tweets using keywords such as "telework," "work from home," "remote work," and so forth, and analyzed the content using natural language processing (NLP) techniques. Sentiment analysis results show generally positive attitudes expressed by remote work-related tweets, with minor dips during the weekend. Topic modeling results uncovered themes among tweets including home office, cybersecurity, mental health, work-life balance, teamwork, and leadership, with minor changes in topics revealed over the 14-week period. Findings point to topics of particular concern regarding working from home and can help guide hypothesis generation for future research. (PsycInfo Database Record (c) 2021 APA, all rights reserved).

Empirical Analysis of Weapons of Influence, Life Domains, and Demographic-Targeting in Modern Spam - An Age-Comparative Perspective.

Spam has been increasingly used for malware distribution. This paper analyzed modern spam from an age-comparative perspective to (i) discover the extent to which psychological weapons of influence and life domains were represented in today's spam emails and (ii) clarify variations in the use of these weapons and life domains by user demographics. Thirty five young and 32 older participants forwarded 18,605 emails from their spam folder to our study email account. A random set of 961 emails were submitted to qualitative content coding and quantitative statistical analysis. Reciprocation was the most prevalent weapon; financial, leisure, and independence the most prevalent life domains. Older adults received health and independence-related spam emails more frequently, while young adults received leisure and occupation-related spam emails more often. These age differences show a level of targeting by user demographics in current spam campaigns. This targeting shows the need for age-tailored demographic warnings highlighting the presence of influence and pretexting (life domains) for suspicious emails for improved response to cyber-attacks that could result from spam distribution. The insights from this study and the produced labeled dataset of spam messages can inform the development of the next generation of such solutions, especially those based on machine learning.

Is ursodeoxycholic acid effective for intrahepatic cholestasis of pregnancy?

Intrahepatic cholestasis of pregnancy is a condition associated with fetal morbidity and mortality. Ursodeoxycholic acid has been proposed as a treatment alternative, but its use remains controversial. Searching in Epistemonikos database, which is maintained by screening 30 databases, we identified three systematic reviews including eight randomized trials. We combined the evidence using meta-analysis and generated a summary of findings table following the GRADE approach. We concluded ursodeoxycholic acid reduces prematurity risk and need for admission in neonatal intensive care units. It might also reduce maternal pruritus.

La colestasia intrahepática del embarazo es una condición propia de la gestación y se asocia a mayor morbilidad y mortalidad perinatal. Dentro de las alternativas terapéuticas se ha propuesto el uso del ácido ursodeoxicólico, sin embargo su beneficio sigue siendo controvertido. Utilizando la base de datos Epistemonikos, la cual es mantenida mediante búsquedas en 30 bases de datos, identificamos tres revisiones sistemáticas que en conjunto incluyen ocho estudios aleatorizados. Realizamos un metanálisis y tablas de resumen de los resultados utilizando el método GRADE. Concluimos que el uso de ácido ursodeoxicólico en la colestasia intrahepática del embarazo podría reducir el riesgo de prematurez y de necesidad de hospitalización del recién nacido en unidad de cuidado intensivo. También podría disminuir el prurito materno.