RESUMO
Immediate and long-term results of parenteral and oral administration of cytoflavin to patients with diabetic foot complicated by grade I and II trophic ulcers (Wagner classification) are considered with special reference to the assessment of reparative processes, normalization of the serum pro oxidant-antioxidant system, and improvement of clinical and instrumental bloodflow characteristics.
Assuntos
Pé Diabético/tratamento farmacológico , Mononucleotídeo de Flavina/farmacologia , Inosina Difosfato/farmacologia , Fármacos Neuroprotetores/farmacologia , Niacinamida/farmacologia , Succinatos/farmacologia , Adulto , Idoso , Combinação de Medicamentos , Feminino , Mononucleotídeo de Flavina/administração & dosagem , Humanos , Inosina Difosfato/administração & dosagem , Masculino , Pessoa de Meia-Idade , Fármacos Neuroprotetores/administração & dosagem , Niacinamida/administração & dosagem , Succinatos/administração & dosagem , Síndrome , Resultado do TratamentoRESUMO
We summarize the literature data on diagnostics of diabetic foot syndrome including clinical examination and special invasive and non-invasive studies of the vascular system. The main methods are ultrasound dopplerography, X-ray contrast angiography, and ultrasound duplex scanning. Special attention is given to instrumental diagnostics of diabetic neuropathies. The golden standard for the evaluation of the function of the peripheral nervous system is electroneuromyography. Methods for the study of diabetic foot complications, such as osteoarthropathy and trophic ulcers, are discussed.