1.
Dokl Akad Nauk SSSR
; 307(6): 1507-11, 1989.
Artigo
em Russo
| MEDLINE
| ID: mdl-2480212
Assuntos
Antígenos CD/imunologia , Antígenos de Diferenciação/imunologia , Imunotoxinas/farmacologia , Leucemia de Células T/patologia , Ricina/farmacologia , Linfócitos T/imunologia , Anticorpos Monoclonais/farmacologia , Antígenos CD5 , Sobrevivência Celular/efeitos dos fármacos , Humanos , Técnicas In Vitro , Leucemia de Células T/imunologia
2.
Bioorg Khim
; 12(6): 819-27, 1986 Jun.
Artigo
em Russo
| MEDLINE
| ID: mdl-3778532
RESUMO
A number of ribavirin analogues were prepared in which the ribose moiety was replaced with acyclic substituents imitating some fragments of the ribose ring: 2,3-dihydroxy-prop-1-yl, 3-hydroxymethyl-4-hydroxy-2-oxabut-1-yl, 4,5-dihydroxy-2-oxapent-1-yl and 1,5-dihydroxy-3-oxapent-2-yl. These analogues were synthesized by direct alkylation of ethyl 1,2,4-triazole-3-carboxylate with suitable agents followed by ammonolysis. New convenient methods for preparing the alkylating agents were developed.