RESUMO
A total of 7 patients with clinical stage C prostate cancer determined by digital rectal examination, transrectal ultrasonography, radionuclide bone scanning and serum prostatic acid phosphatase determination was treated with luteinizing hormone-releasing hormone analogues for 2 to 5 months in an attempt to downstage the disease. Although substantial decreases in prostate specific antigen level and prostatic volume occurred, only 2 patients experienced pathological downstaging of disease. We conclude that luteinizing hormone-releasing hormone therapy for downstaging of clinical stage C prostatic cancer is of limited value.
Assuntos
Hormônio Liberador de Gonadotropina/uso terapêutico , Neoplasias da Próstata/tratamento farmacológico , Idoso , Antígenos de Neoplasias/sangue , Biomarcadores Tumorais/sangue , Preparações de Ação Retardada , Humanos , Masculino , Pessoa de Meia-Idade , Estadiamento de Neoplasias , Antígeno Prostático Específico , Neoplasias da Próstata/sangue , Neoplasias da Próstata/patologiaRESUMO
A case of fibroma of the tunica albuginea is presented with a review of the literature on previously reported cases of this rare entity. The characteristics of this lesion, its pathogenesis, and its treatment are considered.
Assuntos
Calcinose/patologia , Fibroma/patologia , Neoplasias Testiculares/patologia , Adulto , Calcinose/cirurgia , Castração , Fibroma/cirurgia , Humanos , Masculino , Neoplasias Testiculares/cirurgiaRESUMO
A case of plexiform neurofibroma of the lower urinary tract is presented as well as a review of all previously reported cases in childhood. We suggest aggressive management in patients with diffuse disease.
Assuntos
Neurofibroma/cirurgia , Neoplasias da Bexiga Urinária/cirurgia , Pré-Escolar , Humanos , Masculino , Neurofibroma/diagnóstico por imagem , Neurofibroma/patologia , Radiografia , Neoplasias da Bexiga Urinária/diagnóstico por imagem , Neoplasias da Bexiga Urinária/patologiaRESUMO
Two patients with large calculi in solitary kidneys, treated by ex vivo stone extraction and autotransplantation, are presented. The results show this to be a valuable therapeutic modality for difficult renal calculi where an in situ approach would be hazardous.