RESUMO
Angiomatoid fibrous histiocytoma (AFH) is a rare soft tissue tumor most commonly occurring in children, adolescents, and young adults. Clinically and radiographically the lesion is easily confused with a hematoma, soft tissue hemangioma, or malignant fibrous histiocytoma. While the lesion is rare, due to the potential for local recurrence and metastasis, it is imperative to consider this lesion in the differential diagnosis of a soft tissue mass in a child or adolescent. Here, we present the clinical, radiologic, and pathologic findings of a case of AFH.
Assuntos
Histiocitoma Fibroso Maligno/diagnóstico , Histiocitoma Fibroso Maligno/cirurgia , Imageamento por Ressonância Magnética/métodos , Neoplasias de Tecidos Moles/diagnóstico , Neoplasias de Tecidos Moles/cirurgia , Angiomatose , Criança , Feminino , Humanos , Coxa da Perna/patologia , Coxa da Perna/cirurgia , Resultado do TratamentoRESUMO
Rapid detection of vancomycin-resistant enterococci (VRE) carriers could be useful to health care facilities to minimize transmission. To that end, we compared the performance of the Cepheid GeneXpert vanA/vanB assay with that of direct and broth-enriched culture methods for detection of VRE from perianal swabs. Enterococci were cultivated on Enterococcosel™ agar with 8 µg/mL vancomycin, Bile Esculin Azide Agar with 6 µg/mL vancomycin, and Bile Esculin Azide Enterococcosel Broth. Compared to the reference standard (combination of direct agar plating, broth-enriched culture, and clinical chart review), the sensitivity, specificity, positive predictive value, and negative predictive value of the vanA/vanB assay were 96.4%, 93.0%, 92.0%, and 96.9%, respectively (n=184). The 95% limit of detection was 100 colony-forming units (CFU)/mL for vanA and 114 CFU/mL for vanB. In summary, the GeneXpert vanA/vanB assay is a rapid and accurate method to identify vanA/vanB-colonized patients for VRE screening programs that use perianal swab specimens.
