RESUMO
During the months of October and November 2006-2008, norovirus was detected in the stools of 14 children hospitalized with acute diarrhea (no sapovirus). Nine of these noroviruses belonged to a unique GGII4 strain, which produced severe clinical symptoms, present only in 2007 and 2008 and absent in 2006. This strain, identified in Europe mainly in the elderly, seems to be on the rise in children in the Paris area over the past few years.
Assuntos
Infecções por Caliciviridae/epidemiologia , Infecções por Caliciviridae/virologia , Fezes/virologia , Gastroenterite/epidemiologia , Gastroenterite/virologia , Pacientes Internados/estatística & dados numéricos , Norovirus/isolamento & purificação , Adolescente , Infecções por Caliciviridae/diagnóstico , Infecções por Caliciviridae/genética , Criança , Pré-Escolar , Gastroenterite/diagnóstico , Variação Genética , Genótipo , Humanos , Lactente , Norovirus/genética , Paris/epidemiologia , Estudos RetrospectivosRESUMO
OBJECTIVE: To report a case of transitional cell carcinoma of the urethra associated with human papilloma virus (HPV) infection in areas of squamous differentiation of the neoplasm. METHODS/RESULTS: A 32-year-old male with a previously treated condylomata acuminatum of the prepuce presented with a verrucous lesion in the penile meatus, corresponding to well differentiated, low grade papillary transitional cell carcinoma with squamous differentiation. Histological viral expression of HPV was confirmed by in situ hybridization. CONCLUSION: We emphasize the rare presentation of transitional carcinoma in the distal urethra associated with HPV infection.