Treatment for multiple myeloma in hospital at home: clinical characteristics and patient care pathways.

While most patients receive anticancer injection in a conventional hospital, some are treated in hospital at home. Given the lack of data, we seek to determine the clinical characteristics and care pathways of patients benefiting from hospital at home (HAH) for anticancer injection. A longitudinal scheme was conducted about patients with multiple myeloma (MM) starting bortezomib-based regimens in HAH in 2015 with a follow-up to September 2019. 154 patients received bortezomib at home with a mean age of 70.6 years, 72.7% over 65y-old and, a median Karnofsky Performans Status of 70. One-third of the elderly lived alone, 16.1% required domestic help. After a 24-month follow-up, 77.9% of patients were alive. The median overall survival was not reached at 4 years. Between 42.1% and 48.1% of patients returned to HAH for a new line of treatment. Patients were mainly independent and "fit." The involvement of HAH was achieved without safety issues nor compromise long-term outcomes. However, the real-world patterns highlighted that only a small proportion of patients returned to HAH for a new treatment line.

The experience of patients and family caregivers during hospital-at-home in France.

BACKGROUND: Public health policies tend to generalize the use of Hospital-At-Home (HAH) to answer the growing will of patients to be treated or to die at home. HAH is a model of care that provides acute-level services in the patient's home with the interventions of variety of health care professionals. Relatives participate also in the interventions by helping for sick patients at home, but we lack data on the care of patients and caregivers in HAH. The aim of this study was to make an inventory of the experiences of patients and family caregivers in HAH. METHODS: The research was qualitative using nineteen semi-directed interviews from nine patients and ten caregivers of one care unit of Greater Paris University Hospitals' HAH, and the grounded theory was used to analyze the transcripts. Caregivers were also asked, after the interview, to fill in the Zarit Burden Inventory. RESULTS: HAH remained mostly unknown for patients and caregivers before the admission proposition and the outlook of being admitted in HAH was perceived as positive, for both of them. Caregivers had a versatile role throughout HAH, leading to situations of suffering, but also had sources of support. The return home was considered satisfactory by both caregivers and patients, related to the quality of care and increased morale despite HAH's organizational constraints. We noted an impact of HAH on the relationship between the patient and the caregiver(s), but caused by multiple factors: the fact that the care takes places at home, its consequences but also the disease itself. CONCLUSION: HAH strongly involved the patient's caregiver(s) all along the process. HAH's development necessitates to associate both patients and caregivers and to take into account their needs at every step. This study highlights the need to better assess the ability of the caregiver to cope with his or her relative in HAH with acute and subacute care at home.

[Clinical characteristics, care professionals' intervention and care complexity for elderly patients in home hospitalization]. / Soins en HAD : aspects cliniques, complexité et modalités d'intervention des soignants.

INTRODUCTION: The number of elderly patients in home care in France is currently increasing. Our objective is to describe the clinical characteristics, the care professionals' intervention and the complexity of follow-up care for this elderly population. METHODS: This is a cross-sectional study with a sample of 50 elderly patients aged 75 and over living at home and followed-up in home hospitalization in 2016 by the Assistance Publique Hôpitaux de Paris. The collection of data used the interRAI-CA tool (Resident Assessment Instrument - Contact Assessment). RESULTS: The average age of the sample was 84 years with 48% women, 26% living alone and 96% having a caregiver who had difficulty in caring in 33.3% of cases. Patients had numerous diseases with 68% of the sample who had cognitive difficulties with functional disabilities; Most of them reported pain and 52% had unstable clinical situation. The main care interventions were complex wounds, supportive care and palliative care with technical care and 80% of the sample mobilized more than 3 professionals. Care was considered to be of a high level of complexity for 74% of the elderly patients. CONCLUSION: Our study showed that elderly patients had care complexity with technical and multi-faceted care implying coordination of stakeholders and support for caregivers. Implementing at-home hospitalization allows to transfer some geriatric patients from hospitalization to the home care and helps the structuration of the geriatric expertise among the primary care services.

[Clinical characteristics of patients with ALS hospitalised at home]. / Caractéristiques cliniques des patients atteints de SLA en hospitalisation à domicile.

A study was carried out in 2013 in order to describe, using data from the programme for a medicalised information system, the population of patients with amyotrophic lateral sclerosis (ALS) cared for through the hospital at home service of the AP-HP Paris hospital group. This study highlights the highly technical nature of the care, in a context of palliative care and patient dependency. Patient care needs to be coordinated, preferably within a network.

[Palliative care at home: patient care pathways and clinical characteristics]. / Patients en situation palliative en hospitalisation à domicile : trajectoires de soins et caractéristiques cliniques.

INTRODUCTION: The great majority of French people express their desire to receive palliative care at home. The objective of this study was to describe the clinical care pathways and characteristics of patient receiving hospital at home palliative care. METHODS: This study compared the care pathways and clinical characteristics of patients receiving palliative care at home in the Ile-de-France region in 2014. Retrospective data were extracted from the French medical information systems programme. RESULTS: 817 patients receiving palliative care at home were included in the study. They were older, more often referred to hospital at home by a primary care physician, had shorter lengths of stay and more often died at home compared to patients without palliative care. Palliative care patients mainly presented cancer and received frequent technical nursing care. The oldest patients (≥ 75 years old) more often presented neurodegenerative diseases, were less often transferred to hospital, and more often died at home compared to younger patients. A higher proportion of home deaths was observed in nursing home residents and patients who died at home required less technical nursing care. CONCLUSION: This study provides important information concerning admission to hospital at home, the frequent changes of places of care and the complexity of maintaining palliative care at home until the patient's death.

[Impact on professional practices of a care protocol implemented between usual hospital care and hospital at home]. / Impacts sur les pratiques professionnelles d’un protocole de soins mis en place entre l’hospitalisation avec hébergement et l’hospitalisation à domicile.

BACKGROUND: Implementation of a care protocol between usual hospital care and hospital at home (HAH) could improve the quality of care and decrease fragmentations of the French healthcare system. This study evaluated the impact on professional practices of a care protocol implemented between a surgery unit and hospital at home. METHODS: Twenty healthcare professionals (nurses, head nurses, physicians) from HAH and a Paris public hospital urology unit were interviewed by a public heath physician. Semistructured interviews were analyzed using the grounded theory. RESULTS: Professional practices were modified with better traceability of care, greater safety for professionals and for patients, standardization of practices and improved continuity of interventions between hospital and hospital at home. However, these changes in practices appeared to be limited to the protocol itself and indicated potential enhancement of technical aspects to the detriment of human contact. CONCLUSION: This care protocol has an encouraging impact on the quality of care. These results demonstrate the value of extending this approach to other wards to improve continuity of care between usual hospital care and hospital at home.

[Coordination in hospital-based home care]. / Coordination gérontologique en HAD.

Hospital at home involves multidisciplinary teams who provide care 24/7 in the homes of increasingly elderly patients. They present complex medical, mental and social needs with secondary functional incapacities.