External waveguide magnetic resonance imaging for lower limbs at 3 T.

PURPOSE: We report a method based on the traveling-wave MRI approach, in order to acquire images of human lower limbs with an external waveguide at 3 T. METHODS: We use a parallel-plate waveguide and an RF surface coil for reception, while a whole-body birdcage is used for transmission. The waveguide and the surface coil are located right outside the magnet, in the magnetic resonance (MR) conditional devices zone. We ran numerical simulations to investigate the B 1 field generated by the surface coil located at one of the waveguides, as well as a saline-solution phantom positioned on the opposite side (150 cm away) inside the magnet. RESULTS: We obtained phantom images by varying the distance between the coil and the phantom, in order to investigate the signal-to-noise ratio and to validate our numerical simulations. Lower limb images of a healthy volunteer were also acquired, demonstrating the viability of this approach. Standard pulse sequences were used and no physical modifications were made to the MR imager. CONCLUSIONS: These numerical and experimental results show that traveling-wave MRI can produce high-quality images with only a simple waveguide and an RF coil located outside the magnet. This can be particularly favorable when acquiring images of lower limbs requiring a larger field of view.

Remote RF excitation for small-bore MR imager at 15.2 T.

We report a method for remote excitation of the RF signal for preclinical-equivalent ultra high field Magnetic Resonance Imaging (MRI). A parallel-plate waveguide together with a bio-inspired surface coil were used to perform remote excitation experiments to acquire images with a small-bore MR imager at 15.2 T. The imager bore size limits the RF coil transmitter dimensions, so the Gielis super-formula was used to design an RF coil with small dimensions. Electromagnetic simulations of the principal mode were run to study the waveguide filled with air and loaded with a saline solution-filled tube. Radiation patterns were also computed in a semi-anechoic chamber for the same scenarios as above. A saline solution-filled spherical phantom and a formaldehyde-fixed mouse phantom were used to acquire images. Radiation patterns showed an omnidirectional distribution with no side lobes, and a very smooth behaviour with almost no loss of information in the saline solution-filled tube and without. The theoretical wave impedance was calculated and compared with simulated results showing an excellent correspondence. Spherical phantom image data and simulation results of B1 were contrasted and showed an important correlation. Ex vivo mouse images were of high quality and exhibited clear delineation of anatomical structures. These imaging results are in very good agreement with the simulations. Numerical, theoretical and experimental results validate this approach, using a bio-inspired surface coil with a simple waveguide for preclinical small-bore MRI at ultra high field.

A new index measured by cardiovascular magnetic resonance imaging to detect mechanical heart valve malfunction.

More than two thirds of valve replacement operations performed each year used mechanical heart valve. These valves are subject to complications such: pannus and/or thrombus formation. One other potential complication is a malfunction in one of the valve leaflets. It is then important to develop parameters that will allow a non-invasive diagnosis of such valve malfunction. In the present study, we evaluated under steady low flow (1-8 L/min) and pulsatile flow (3, 5 and 7 L/min) a bileafleat mechanical heart valve with normal function, 50% and 100% of one valve leaflet malfunction. Image analysis was performed using cardiovascular magnetic resonance imaging to evaluate transvalvular pressure gradients (TPG), effective orifice area and a new index given by central/lateral velocity ratio downstream of the valve. Our results showed that the flow upstream and downstream of the defective valve is highly influenced by malfunction severity. TPG did not allow differentiating valve malfunction at low flow under steady and pulsatile conditions. However the new index given by central/lateral ratio allowed differentiating the presence of valve malfunction using a single transverse velocity measurement.

Study of optimal separation of two circular phased-array coils via an equivalent circuit.

The coil separation of phased-array coils is an important issue if a wide area of interest is to be imaged. An equivalent circuit of two circular-shaped coils was used to compute the optimal distance in a two phased-array coil. This circuit included the mutual inductance of two circular coils. An expression for the mutual inductance was derived and the resulting values included in the circuit. With all these elements an equivalent circuit of two overlapped circular coils was built to simulate a phased-array coil. To find a solution to this circuit, specifically written programmes in Spice Opus Light were used. Optimal separations were calculated from separation-vs-attenuation for different coil radii. Results compare very well with those reported in the literature.