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2.
J Career Assess ; 30(3): 573-589, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-38603163

RESUMO

This paper highlighted the diverse voices of 84 female-identifying professors in STEM fields who responded to a series of open-ended questions regarding work, family, and tenure experiences in the context of the current global pandemic. The current paper is part of a longitudinal study of the vocational experiences of tenure-track women in STEM that has examined the "leaky pipeline" in women's academic careers. Consensual Qualitative Research-Modified (CQR-M; ) was implemented to analyze the data. The findings suggested that participants perceived the precarious balance between work and family to have increased in difficulty in the face of COVID-19. Among untenured female faculty with children, an added layer of challenge was noted related to loss of childcare in the wake of the pandemic. The pre-existing, pervasive barriers (i.e., institutional, systemic, and psychological) were further exacerbated by familial barriers for female STEM faculty seeking tenure during COVID-19. Overall, the results indicated missed opportunities within higher education to implement supportive policies for untenured female faculty in STEM. Clinical implications, future research directions, and social advocacy interventions in the context of COVID-19 are discussed.

3.
Eat Weight Disord ; 26(8): 2545-2553, 2021 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-33548052

RESUMO

PURPOSE: A considerable number of post-bariatric surgery patients report problematic eating behaviors (PEBs) and/or eating disorders (EDs). Examining psychosocial variables associated with ED symptoms may identify targets for postoperative interventions to reduce these behaviors and improve surgical outcomes. METHODS: A total of 161 participants completed the Minnesota Multiphasic Personality Inventory-2-Restructured Form (MMPI-2-RF) and the Eating Disorder Examination-Questionnaire (EDE-Q). Participants were classified into ED risk or no ED risk groups and subjective binge eating (SBE) or no SBE groups. Independent-sample t tests were computed to examine mean differences in total weight loss (%TWL) and MMPI-2-RF scale scores between the ED groups. Relative Risk Ratios (RRRs) were computed to determine which MMPI-2-RF scales were associated with increased risk of ED group membership. RESULTS: The ED risk group lost significantly less weight (19.36% TWL) than the no ED risk group (25.18% TWL). The SBE group lost significantly less weight (17.98% TWL) than the no SBE group (25.57% TWL). Participants in the ED groups scored significantly higher on internalizing and externalizing MMPI-2-RF scales than the no ED groups. These scales were associated with increased risk (1.55-2.55 times the risk) of being classified into the ED groups. CONCLUSIONS: Patients who experienced postoperative ED symptoms lost significantly less weight than patients without ED symptoms. Postoperative ED symptoms are related to, and may be impacted by, higher levels of internalizing and externalizing dysfunction after surgery. Postoperative assessment of and interventions targeting psychosocial dysfunction could decrease ED symptoms. LEVEL OF EVIDENCE: III: Evidence obtained from well-designed cohort or case-control analytic studies.


Assuntos
Cirurgia Bariátrica , Transtornos da Alimentação e da Ingestão de Alimentos , Obesidade Mórbida , Humanos , MMPI , Redução de Peso
4.
PLoS One ; 11(5): e0154730, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-27182599

RESUMO

Provenance studies are an increasingly important analog for understanding how trees adapted to particular climatic conditions might respond to climate change. Dendrochronological analysis can illuminate differences among trees from different seed sources in terms of absolute annual growth and sensitivity to external growth factors. We analyzed annual radial growth of 567 36-year-old pitch pine (Pinus rigida Mill.) trees from 27 seed sources to evaluate their performance in a New Jersey Pine Barrens provenance experiment. Unexpectedly, missing rings were prevalent in most trees, and some years-1992, 1999, and 2006-had a particularly high frequency of missing rings across the plantation. Trees from local seed sources (<55 km away from the plantation) had a significantly smaller percentage of missing rings from 1980-2009 (mean: 5.0%), relative to northernmost and southernmost sources (mean: 9.3% and 7.9%, respectively). Some years with a high frequency of missing rings coincide with outbreaks of defoliating insects or dry growing season conditions. The propensity for missing rings synchronized annual variations in growth across all trees and might have complicated the detection of potential differences in interannual variability among seed sources. Average ring width was significantly larger in seed sources from both the southernmost and warmest origins compared to the northernmost and coldest seed sources in most years. Local seed sources had the highest average radial growth. Adaptation to local environmental conditions and disturbances might have influenced the higher growth rate found in local seed sources. These findings underscore the need to understand the integrative impact of multiple environmental drivers, such as disturbance agents and climate change, on tree growth, forest dynamics, and the carbon cycle.


Assuntos
Meio Ambiente , Pinus/crescimento & desenvolvimento , Clima , Mudança Climática , Ecologia , Florestas , Geografia , New Jersey
5.
Pharmacogenet Genomics ; 26(3): 126-32, 2016 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-26727275

RESUMO

OBJECTIVE: The aim of this study was to determine the possible relationship between the Sp1 polymorphism of gene COL1A1 and bone metabolism disorder in individuals with epilepsy. METHODS: To this end, we carried out an observational cross-sectional study on 64 patients in monotherapy with an antiepileptic drug. The patients were classified on the basis of the presence of the 's' allele of the COL1A1 Sp1 polymorphism. RESULTS: In the patients with SS, the standardized bone mineral density (sBMD) in the left femoral neck was 1024.9±206.1 mg/cm, whereas in the patients with Ss or ss, the density was significantly lower, 917±141.4 mg/cm (P=0.027), as was the femoral t-score (0.72±1.67 vs. -0.29±1.15, P=0.01). The values in the lumbar spine were equally greater in those with SS: 1219.1±236.3 versus 1090.5±142.7 mg/cm for the sBMD (P=0.018) and 0.67±1.98 versus -0.34±1.16 for the lumbar t-score (P=0.023). The bone biomarkers showed no significant differences nor did the 25-OH vitamin D and parathormone values. In the patient group treated with valproic acid (VPA), the densitometric values were significantly lower in the Ss or ss patients compared with SS homozygotes: 887.1±142.6 versus 1120.6±198.2 mg/cm for femoral sBMD (P=0.02), 990±98.1 versus 1417±251.2 mg/cm for lumbar sBMD (P=0.001). Of the patients who were carriers of the 's' allele and who were treated with VPA, 86% achieved osteopenia values. CONCLUSION: In our study, the presence of the 's' allele of the COL1A1 Sp1 polymorphism in individuals with epilepsy was related to lower bone BMD (lumbar and femoral). This relationship seemed to be further apparent in the patients undergoing treatment with VPA.


Assuntos
Anticonvulsivantes/administração & dosagem , Densidade Óssea/efeitos dos fármacos , Colágeno Tipo I/genética , Epilepsia/tratamento farmacológico , Polimorfismo de Nucleotídeo Único , Ácido Valproico/administração & dosagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Anticonvulsivantes/farmacologia , Cadeia alfa 1 do Colágeno Tipo I , Estudos Transversais , Epilepsia/genética , Feminino , Colo do Fêmur/efeitos dos fármacos , Colo do Fêmur/patologia , Predisposição Genética para Doença , Humanos , Vértebras Lombares/efeitos dos fármacos , Vértebras Lombares/patologia , Masculino , Pessoa de Meia-Idade , Ácido Valproico/farmacologia , Adulto Jovem
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