RESUMO
The benefits and feasibility of progressive resistance training on muscle strength and bleeding profile were studied prospectively in two patients with severe haemophilia. Additionally, retrospective data were collected from three patients who had been training for 11-21 years (one patient for 21 years and two patients for 11 years). Muscle strength increased, especially in muscle groups surrounding the target joints (elbow and knee). Bleeding frequency decreased from 2-3 times per week to 1-2 times per week. Patients who had been training for > 11 years reported bleeding episodes of 2-4 times per month prior to training, but after > 11 years of progressive training a marked decrease in bleeding occurred, as well as a decrease in severity. These data support the importance of resistance training for haemophilia patients, not only for increasing muscle strength, but also for decreasing the frequency and severity of bleeding episodes and the associated pain. A controlled study, with a greater number of patients, is needed to confirm the suggested benefits of resistance training in haemophilia patients.
Assuntos
Hemofilia A/complicações , Hemorragia/prevenção & controle , Educação Física e Treinamento , Adulto , Saúde da Família , Hemofilia A/fisiopatologia , Hemofilia A/terapia , Hemorragia/etiologia , Hemorragia/terapia , Humanos , Músculo Esquelético/fisiologia , Aptidão Física , Projetos Piloto , Estudos Prospectivos , Amplitude de Movimento Articular , Estudos Retrospectivos , Levantamento de PesoAssuntos
Fator VIII/genética , Rearranjo Gênico , Triagem de Portadores Genéticos , Hemofilia A/diagnóstico , Hemofilia A/genética , Southern Blotting , Inversão Cromossômica , Troca Genética , Desoxirribonucleases de Sítio Específico do Tipo II , Éxons , Feminino , Humanos , Íntrons , Masculino , Linhagem , Polimorfismo de Fragmento de RestriçãoRESUMO
Sonography was performed on 23 hemophilic patients presenting with positive iliopsoas sign. In 21 of these patients sonography confirmed the presence of hematomas. Comparison of the presumed clinical location and the sonographic location, however, revealed a significant discrepancy. Only seven of 15 hematomas that were clinically suspected to be in the iliopsoas muscle were confirmed by sonography at that location. Of the remaining cases, three were localized in the hip joint, one in the proximal thigh, one in the abdominal wall, and one in the iliac fossa. Hemorrhage was not found in two cases. This study indicates that sonography provides valuable information about the site of hematoma in these patients.
