RESUMO
120 imported cases of malaria and 2 cases of malaria among the native population (1986-1987) likely infected by parasite carriers were registered over a period from 1970 to 1988 in Georgia. The attention has been focused on the planning of preventive measures. Parasitological service of the sanitary epidemiological stations is being improved. Population of anophelogenic reservoirs with the larvae-eating fish Gambusia (brought from Italy by N. P. Rukhadze in 1925) seems to be of great importance. Population of reservoirs with Gambusia is widely resorted to in Georgia. This measure has put an end to environmental contamination with insecticides. Complex preventive measures against malaria can ensure a stable situation with the disease in Georgia.
Assuntos
Malária/prevenção & controle , Plasmodium vivax , Animais , Anopheles , Ciprinodontiformes , Reservatórios de Doenças , Ecologia , República da Geórgia , Humanos , Insetos Vetores , Controle de Mosquitos/métodosAssuntos
Toxoplasmose/diagnóstico , Adulto , Erros de Diagnóstico , Reações Falso-Positivas , Feminino , Humanos , Masculino , Testes SorológicosAssuntos
Necatoríase/tratamento farmacológico , Pamoato de Pirantel/uso terapêutico , Pirantel/análogos & derivados , Adolescente , Adulto , Criança , Pré-Escolar , Avaliação de Medicamentos , Tolerância a Medicamentos , Feminino , Humanos , Masculino , Pamoato de Pirantel/administração & dosagem , Fatores de TempoRESUMO
Comparative electron microscopic investigations of Brucella were carried out in cultures in vitro and in vivo in guinea pigs with experimental brucellosis (blood) and in patients with brucellosis. Morphological differences in the structure of brucella due to different environments were found. The authors discuss facultative intracellular parasitism with intraphagosomal reproduction of the causative agent. This form of incompleted phagocytosis is a morphological manifestation of decreased defence properties of cells and causes the development of persistent infection with severe bacteriotoxemia. This is an important factor of the pathogenicity of this agent and underlies the pathogenesis of brucellosis.