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1.
J Biomed Biotechnol ; 2011: 761593, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21274404

RESUMO

The aim of this study was assess the effect of collagen-based films containing usnic acid as a wound dressing for dermal burn healing. Second-degree burn wounds were performed in forty-five Wistar rats, assigned into nine groups: COL-animals treated with collagen-based films; PHO-animals treated with collagen films containing empty liposomes; UAL-animals treated with collagen-based films containing usnic acid incorporated into liposomes. After 7, 14, and 21 days the animals were euthanized. On 7th day there was a moderate infiltration of neutrophils, in UAL, distributed throughout the burn wounds, whereas in COL and PHO, the severity of the reaction was slighter and still limited to the margins of the burn wounds. On the 14th day, the inflammatory reaction was less intense in UAL, with remarkable plasma cells infiltration. On the 21st day, there was reduction of the inflammation, which was predominantly composed of plasma cells in all groups, particularly in UAL. The use of the usnic acid provided more rapid substitution of type-III for type-I collagen on the 14th day, and improved the collagenization density on the 21st day. It was concluded that the use of reconstituted bovine type-I collagen-based films containing usnic acid improved burn healing process in rats.


Assuntos
Benzofuranos/administração & dosagem , Curativos Biológicos , Queimaduras/terapia , Colágeno/administração & dosagem , Lipossomos/administração & dosagem , Cicatrização/efeitos dos fármacos , Actinas/metabolismo , Animais , Queimaduras/metabolismo , Queimaduras/patologia , Colágeno Tipo I/metabolismo , Colágeno Tipo III/metabolismo , Imuno-Histoquímica , Inflamação/patologia , Inflamação/prevenção & controle , Masculino , Miofibroblastos/metabolismo , Ratos , Ratos Wistar
2.
Psychol Sci ; 11(6): 511-4, 2000 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-11202499

RESUMO

When making explicit self-report ratings, members of status- and racial-minority groups report less personal experience with discrimination than that encountered by their group--a phenomenon called the personal/group discrimination discrepancy (PGDD). This study provides evidence, for the first time, that the PGDD may be, in part, a product of the procedure used to measure it. White women and men completed explicit and implicit measures of personal and group discrimination based on sex. The PGDD surfaced among women in the explicit measures, but not in the implicit measures. These findings suggest that explicit and implicit measures might provide different assessments of experience with discrimination.


Assuntos
Individualidade , Preconceito , Identificação Social , Adulto , Feminino , Humanos , Masculino
3.
J Pers Soc Psychol ; 77(4): 774-84, 1999 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-10531671

RESUMO

Members of high-status groups are more likely than members of low-status groups to blame their failure on discrimination and are less likely to blame it on themselves. This tendency was demonstrated in 3 experiments comparing men and women, White and Black students, and members of experimentally created high- and low-status groups. Results also showed that when making an attribution to discrimination, high-status group members were less likely to experience a threat to their social state self-esteem, performance perceived control, and social perceived control and were more likely to protect their performance state self-esteem. These findings help to explain why high-status group members are more willing to blame their failure on discrimination by showing that it is less harmful for them than for low-status group members.


Assuntos
Preconceito , Classe Social , Adulto , Negro ou Afro-Americano/psicologia , Feminino , Humanos , Masculino , Distribuição Aleatória , Autoimagem , População Branca/psicologia
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