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Biosci Biotechnol Biochem ; 88(2): 203-205, 2024 Jan 24.
Artigo em Inglês | MEDLINE | ID: mdl-37947260

RESUMO

Licking behavior with various salts in transmembrane channel-like 4 (Tmc4) knockout (KO) mice was observed. In Tmc4 KO mice, a significant decrease in sensitivity to chloride salts, such as NaCl, KCl, and NH4Cl, was observed, while no significant decrease in sensitivity to Na-gluconate was observed. This finding suggests that TMC4 may be involved in the detection of chloride taste.


Assuntos
Cloretos , Sais , Animais , Camundongos , Amilorida , Camundongos Knockout , Cloreto de Potássio/farmacologia , Paladar
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