RESUMO
OBJECTIVES: To verify the effectiveness of support power of underwear (the shaper) to elevate bladder neck and to reduce symptoms of stress urinary incontinence (SUI). METHODS: This was a single-arm pilot study conducted in Japan by using the shaper (SLIM-up-Pants with Style Science, Wacoal Corporation, Kyoto, Japan). The bladder neck position in a sitting posture was recorded using an open-configuration magnetic resonance system and then compared between parous women with SUI, without and with the shaper. Women wore the shaper during the daytime for 12 weeks, followed by one week during which they did not wear the shaper. The symptoms of urinary incontinence (UI) were assessed based on the 1-h pad test, the Japanese version of the International Consultation Incontinence Questionnaire-Short Form, and the incontinence diary. RESULTS: Forty-five Japanese women with SUI, aged between 27 and 65 years, were included. When the shaper was worn, the bladder neck was found to be significantly elevated by 11.5 mm (median; P < 0.05/6 = 0.008). After 12 weeks, all symptoms of UI decreased significantly (P < 0.05/3 = 0.016), and the bladder neck was further elevated by 4.7 mm (median; P < 0.001) even when not wearing the shaper. In addition, after one week of not wearing the shaper, the bladder neck position remained elevated and symptoms of UI did not recur immediately. CONCLUSION: The shaper was considered to be effective in elevating the bladder neck and reducing symptoms of UI.
RESUMO
INTRODUCTION: Folate deficiencies may be linked to depressive disorders among persons suffering from neurological and psychiatric problems. The purpose of the present study was to evaluate the impact of dietary folate intake on depressive symptoms in young Japanese women of reproductive age. METHODS: The study was conducted in Japan in 2009 with 141 Japanese women aged 18 to 28 years. A Japanese version of the Center for Epidemiologic Studies Depression (CES-D) scale was used to screen for depressive symptoms. Dietary intake was investigated by a diet history questionnaire. Nonfasting blood samples were collected from the women to measure folate and homocysteine levels. RESULTS: The proportion of women with lower folate intake (< 240 µg/d) was significantly higher in the women with CES-D scores greater than or equal to 19 when compared with the folate levels in those with CES-D scores less than 19 (75.0% vs 43.6%, respectively; P < .001). Logistic regression analysis revealed significant associations between CES-D scores greater than or equal to 19, low folate intake, and low vitamin B(6) intake when adjusted for age, living status, smoking, and body mass index. Adequate folate intake of more than the recommended dietary allowance (RDA) level of 240 µg per day was independently related to a decreased risk of depression (adjusted odds ratio 0.22; 95% confidence interval, 0.11-0.56; P < .001). DISCUSSION: Multiple logistic regression analysis revealed a reduced incidence of depression in women whose intake of folate exceeded the RDA of 240 µg per day. This finding suggests that dietary folate intake may be causally related to depressive symptoms in women of reproductive age. If results of studies powered to determine causal relationships are similarly positive, folate supplementation could reduce the incidence of depression.
