Efficacy of neuropsychological rehabilitation on numerical and calculation abilities: A developmental case study.

Present single case proves the effectiveness of a theory-based cognitive treatment on numerical and calculation abilities in developmental age. Both evaluation and treatment were designed on the bases of current models of numerical cognition, in particular Von Aster's developmental model. At the age of 7.4 years, HT was referred for a serious delay in the acquisition of numerical skills involving all numerical and calculation skills (written calculations, numerical knowledge, accuracy, rapidity). Following the rules of neuropsychological rehabilitation, HT was submitted to an early, intensive, HT-tailored treatment based on analogic representation of amount. After 12 months of treatment, HT showed statistically significant increasing in all the investigated variables: however, even if he correctly performed various numerical tasks, he remained significantly slower compared to his peers. Present case demonstrated the efficacy of theory-based, individually-tailored developmental dyscalculia. Early diagnosis and early intervention are urgently needed to get clinically significant change and to prevent behavioral and emotional symptoms.

Semantic abilities predict expressive lexicon in children with typical and atypical language development.

In this study we used a semantic battery assessing the conceptual, lexical, and metacognitive level in semantic relationships to predict expressive lexicon in preschool children with typical and atypical language development. Our regression analyses showed that the tests of our semantic battery altogether accounted for 24% of variance in expressive lexicon after controlling for age and phonological short-term memory. The ability to memorize picture-cue/word pairs that were linked by taxonomic relations made a unique contribution to the expressive lexicon, and was a reliable marker of delayed expressive vocabulary in a group of children with specific language impairment.

Panayiotopoulos syndrome: a clinical, EEG, and neuropsychological study of 93 consecutive patients.

PURPOSE: To explore the clinical, electroencephalography (EEG), neuropsychological features, and prognosis of Panayiotopoulos syndrome (PS). METHODS: Of 1,794 children aged between 1 and 14 years referred for the first afebrile focal seizure, between January 1992 and December 2004, 93 (5.2%) had PS according to clinical criteria. RESULTS: Age at onset ranged from 1.1 to 8.6 years, and was earlier in children with more than one seizure. Autonomic seizures followed a stereotypical onset and progression. Emesis, pallor, or flushing was almost always among the first symptoms that usually culminated in vomiting (77.4% of patients). More than half (55%) of seizures were longer than 30 min but these did not appear to affect remission and number of seizures. Interictal EEG showed great variability, with 79.5% of patients showing spikes of variable localizations and evolution over time; 16.1% had background abnormalities only, and 5.4% had consistently normal EEG studies. Onsets in five ictal EEGs were posterior or anterior-left or right. On neuropsychological testing, IQ and subtests of Wechsler Intelligence Scale for Children-Revised (WISC-R) were within normal limits, although some minor statistically significant differences were found in arithmetic, comprehension, and picture arrangement in comparison with controls. Cumulative probability of recurrence was 57.6%, 45.6%, 35.1%, and 11.7% at 6, 12, 24, and 36 months, respectively, after the first seizure. Thirty-four (58.6%) of 59 patients treated with antiepileptic drugs continued having seizures before ultimate remission. DISCUSSION: PS is a uniform childhood susceptibility to autonomic seizures that is related to early age of development and with excellent prognosis with regard to seizure remission and neuropsychological development.

Contribution of right hemisphere to visual imagery: a visual working memory impairment?

Visual Imagery is the ability to generate mental images in the absence of perception, that is, We describe a patient, IM, who suffered from an acute ischemic stroke in the right anterior choroidal artery who appeared to demonstrate relatively isolated impairment in visual imagery. Her cognitive function, including her performance on tests of semantic function, was at ceiling, apart from a deficit in visual memory. IM failed in tasks involving degraded stimuli, object decision involving reality judgments on normal animals, and drawings from memory. By contrast, she was able to match objects seen from an unfamiliar viewpoint and to perform tasks of semantic and visual association. We hypothesize that IM has a visual working memory deficit that impairs her ability to generate full visual representations of objects given their names, individual feature, or partial representations. The deficit appears to be the result of damage to connections between the right thalamus and the right temporal lobe. Our findings may help to clarify the role of the thalamus in the cortical selective engagement processes that underlie working memory.