[Changes in immunological reactivity during the use of enterosorption in combined treatment of children with severe burns]. / Izmenenie immunologicheskoi reaktivnosti organizma pri primenenii énterosorbenta v komplekse lecheniia detei s tiazhelymi ozhagami.

In 20 children with severe and extremely severe burns since the 3-4th day the enterosorption in the treatment complex was applied. The enterosorbents application have promoted the intoxication severity lowering, the decrease of the damaging action of blood formed elements on the erythrocytes of their own, the lowering of plasma toxic properties, rosette level in peripheral blood. On the 16-18th day after injury the red blood indexes have normalized, allowing to prepare the patients to the operative treatment.

[Effects of enterosorption on the activity of natural-resistance humoral factors in patients with burns]. / Vliianie énterosorbtsii na aktivnost' gumoral'nykh faktorov estestvennoi rezistentnosti organizma postradavshikh s ozhogami.

The data suggesting the enterosorbent influence on the activity of proteolysis inhibitors and arginase, on the fibrin-fibrinogen and fibronectin decay products content, blood serum toxin fixating activity of injured with the burns were presented. The dependence of expression of mentioned indexes changes from the trauma severity in acute burn disease period was shown. The enterosgel application promotes the lowering of dystrophic degree severity, alike the hepar and fixed macrophage system load, the investigated indexes normalization acceleration, and patients condition improvement.

[Efficacy of the use of a stabilized alpha2-macroglobulin concentrate in experimental burns]. / Effektivnost' primeneniia stabilizirovannoi kompozitsii kontsentrata alpha2-makroglobulina pri ozhogovoi bolezni v éksperimente.

The effectiveness of the use of a stabilized composition of alpha 2-macroglobulin concentrate obtained from fraction III of plasma proteins according to Cohn in burn disease in the experiment on guinea pigs was studied. Under the influence of intraabdominal administration for 4 days of alpha 2-macroglobulin concentrate with a stabilizer, healing of the burn wounds, normalization of a state of the animals occurred 2 times more rapidly than in control ones, activity of acid proteinases restored by day 5 (in control--by day 14) due to increase in activity of proteolytic enzyme inhibitors.