[Laboratory diagnosis of myocardial microlesions during coronary balloon angioplasty with stenting].

Fifty patients with stable angina who had undergone elective coronary angioplasty with stenting were examined. Myocardial microlesions diagnosed from the elevated levels of troponin (Tn) I and creatine phosphate kinase MB (CPK-MB) were detected in 48-54% of the patients; however, the content of Tn I exceeded the high reference level only in 18%. Tn I is a more specific method than CPK-MB in detecting myocardial microlesions during intracoronary intervention. The signs of myocardial microlesions were most commonly detected during intervention into the arteries with types B and C stenoses in case of complicated or technically difficult stent implantation.

[The effect of the inhalation of ethanol and acetone on the indices of the antioxidant protection system and on lipid peroxidation in the brain tissue and blood serum of rats]. / Vliianie ingaliatsii étanola i atsetona na pokazateli sistemy antioksidantnoi zashchity i perekisnoe okislenie lipidov tkani mozga i syvorotki krovi krys.

Ethanol or acetone inhalation resulted in a reduction in motor activity in rats, affecting largely their explorative behavior. The biochemical parameters of free-radical processes (catalyse and SOD activities, LPO levels) remained unchanged in the inhaling animals. Ethanol or acetone inhalation caused a significant decrease in blood catalyse activity and serum LPO levels. The acetone- and ethanol-induced changes in the activity of ceruloplasmin were heterodirectional. It can be concluded that it is useful to study the biochemical parameters of serum free-radical processes and to employ the findings in the therapy of inhalation toxicomanias.