[Karyological and immunological parameters in children under conditions of varying ambient air pollution].

The cytological status, proliferation, and apoptosis of the buccal epithelium and the level of secretory immunoglobulin A were studied in 90 children living in a large ferrous metallurgy center (Tula). There were increases in the degree of cytogenetic impairments, a change in cell kinetic processes, and a reduction in local immunity in children in a more polluted area. There was a high significant correlation of karyological and immunological parameters with some chemical ambient air pollutants.

[Multifactorial analysis of risk factors for lung cancer in the city of Tula]. / Kompleksnaia otsenka faktorov riska zabolevaniia rakom lëgkikh u zhitelei g. Tuly.

A multifactorial epidemiologic study of high incidence of lung cancer was conducted in the city of Tula. Mathematical methods of pattern recognition were used. The influence of 20 factors of risk was evaluated. The leading ones were tobacco smoking, occupational exposure to carcinogenic substances and precancerous lesions in the lungs. The influence of industrial pollution on cancer morbidity was assessed as moderate. Mathematical estimates for effectiveness of correction of "controllable" risk factors were given.