RESUMO
As the prevalence of human immunodeficiency virus (HIV) infection continues to rise the clinician is encountered with a diagnostic challenge. Nonsurgical diseases such as acute colitis or enteritis can appear similar to such true surgical emergencies as abscess, perforation, or mesenteric ischemia. We report a case of fulminant hepatic failure associated with didanosine and masquerading as a surgical abdomen and compare the clinical, biologic, histologic, and ultrastructural findings with reports described previously. This entity should be kept in mind when evaluating the acute abdomen in the HIV-positive patient.
Assuntos
Acidose Láctica/diagnóstico , Fármacos Anti-HIV/efeitos adversos , Didanosina/efeitos adversos , Fígado Gorduroso/induzido quimicamente , Infecções por HIV/tratamento farmacológico , Falência Hepática/induzido quimicamente , Abdome Agudo/diagnóstico , Adulto , Diagnóstico Diferencial , Fígado Gorduroso/patologia , Fígado Gorduroso/cirurgia , Feminino , Humanos , Fígado/patologia , Falência Hepática/cirurgiaRESUMO
A 3-year-old Algerian boy with unusual facies, mesomelic dysplasia of the upper extremities, meta-epiphyseal changes in the lower extremities and skin dimples is reported. The authors are not able to classify the child's syndrome nosologically.
Assuntos
Anormalidades Múltiplas , Braço/anormalidades , Osteocondrodisplasias/diagnóstico por imagem , Osso e Ossos/diagnóstico por imagem , Pré-Escolar , Face/anormalidades , Humanos , Masculino , Radiografia , SíndromeRESUMO
An unusual case of multicentric/multifocal osteolysis with unique clinical and radiographic features in a 17-year-old girl is reported. The brother of the patient who was probably also affected could not be examined.
Assuntos
Osteólise Essencial , Adolescente , Osso e Ossos/patologia , Feminino , Humanos , Cifose/patologia , Osteólise Essencial/patologia , Escoliose/patologiaRESUMO
A 6-year-old Algerian boy with "caudal regression syndrome" and spondylo-epiphyseal dysplasia is reported. We believe this represents a new malformation syndrome or a random association of two non-related entities.
Assuntos
Doenças do Desenvolvimento Ósseo , Osteocondrodisplasias , Sacro/anormalidades , Pré-Escolar , Pé Torto Equinovaro , Ossos Faciais/anormalidades , Incontinência Fecal , Humanos , Masculino , Síndrome , Bexiga Urinaria NeurogênicaRESUMO
A new, dominantly inherited form of peripheral dysplasia in three members of an Algerian family is reported. Two further individuals, not investigated, are also probably affected. The disease is characterised by distinctive clinico-radiological findings. A case of acromesomelic dysplasia of Maroteaux is also reported and the differential diagnosis of peripheral dysplasias is discussed.
Assuntos
Genes Dominantes , Osteocondrodisplasias/genética , Adulto , Estatura , Criança , Diagnóstico Diferencial , Feminino , Humanos , Inteligência , Masculino , Osteocondrodisplasias/diagnóstico por imagem , Radiografia , SíndromeAssuntos
Calcinose/diagnóstico , Artropatias/diagnóstico , Adolescente , Calcinose/diagnóstico por imagem , Calcinose/patologia , Criança , Pré-Escolar , Feminino , Humanos , Recém-Nascido , Artropatias/diagnóstico por imagem , Artropatias/patologia , Masculino , Tomografia Computadorizada por Raios XRESUMO
Two siblings who represent a new type of acro-mesomelic dysplasia are reported. The unique pattern of the acro-mesomelic hypoplastic/dysplastic changes allows us to designate them as a new syndrome.
Assuntos
Osteocondrodisplasias/genética , Criança , Feminino , Humanos , Masculino , Osteocondrodisplasias/diagnóstico por imagem , Radiografia , SíndromeRESUMO
A new, dominantly inherited, severe form of spondylometaphyseal dysplasia in five members of an Algerian family is reported. Another child, not investigated, was also probably affected. The disease is characterised by a unique clinical and radiological set of features: dwarfism, genu valgum deformity, progressive kypho-scoliosis, wrist deformity, myopia and severe metaphyseal dysplasia, with moderate spinal changes and minimal changes in the hands and feet. In view of the geographical localisation of the disorder and the anatomical distribution we propose the name Algerian type of spondylo-metaphyseal dysplasia.
