Assuntos
Amiloidose/etiologia , Artrite Reumatoide/complicações , Psoríase/complicações , Amiloidose/imunologia , Amiloidose/patologia , Artrite Reumatoide/imunologia , Artrite Reumatoide/patologia , Feminino , Humanos , Técnicas Imunoenzimáticas , Masculino , Pessoa de Meia-Idade , Psoríase/imunologia , Psoríase/patologia , Proteína Amiloide A Sérica/análiseAssuntos
Ectima Contagioso/etiologia , Infecções Tumorais por Vírus/etiologia , Criação de Animais Domésticos , Animais , Papillomavirus Bovino 1 , Bovinos , Doenças dos Bovinos/microbiologia , Ectima Contagioso/microbiologia , Humanos , Masculino , Pessoa de Meia-Idade , Doenças Profissionais/etiologia , Ovinos , Infecções Tumorais por Vírus/microbiologia , ZoonosesRESUMO
Hepatic porphoria and histologically verified cirrhosis, teleangiectasia, purpose, papular skin lesions existing for eight years, as well as cryomacroglobulin were found in a 49 year old man. Pathogenetically the liver disease is considered to be the primary event, which was accompanied by secondary cryoglobulinemia. IgG and IgM type of thrombus in the vessels and of small granular deposits corresponding to the type of cryoprotein in the blood, were detected in the vessel walls of the upper part in the dermis and along these vessels of both purpuri and papular skin lesions. Immunoprecipitates could be revealed by FTC-labelled antihuman complement. In the skin lesions porphyrin could not be demonstrated. The investigation of cryoglobulin and of porphyrin disorders is reasonable in every patient with purpura accompanying pathological liver processes.