1.
J Org Chem
; 83(8): 4775-4785, 2018 04 20.
Artigo
em Inglês
| MEDLINE
| ID: mdl-29595976
RESUMO
We have studied the reactions of o-quinone methide precursors with imino ethers. The reaction provides a versatile route to substituted 1,3-benzoxazines. The proposed reaction mechanism involves the generation of the o-quinone methide intermediates, imino-Diels-Alder reaction, and elimination. This cascade process is a rare example of the participation of imino ethers as dienophiles.