Fate and transport modelling for evaluating antibiotic resistance in aquatic environments: Current knowledge and research priorities.

Antibiotics have revolutionised medicine in the last century and enabled the prevention of bacterial infections that were previously deemed untreatable. However, in parallel, bacteria have increasingly developed resistance to antibiotics through various mechanisms. When resistant bacteria find their way into terrestrial and aquatic environments, animal and human exposures increase, e.g., via polluted soil, food, and water, and health risks multiply. Understanding the fate and transport of antibiotic resistant bacteria (ARB) and the transfer mechanisms of antibiotic resistance genes (ARGs) in aquatic environments is critical for evaluating and mitigating the risks of resistant-induced infections. The conceptual understanding of sources and pathways of antibiotics, ARB, and ARGs from society to the water environments is essential for setting the scene and developing an appropriate framework for modelling. Various factors and processes associated with hydrology, ecology, and climate change can significantly affect the fate and transport of ARB and ARGs in natural environments. This article reviews current knowledge, research gaps, and priorities for developing water quality models to assess the fate and transport of ARB and ARGs. The paper also provides inputs on future research needs, especially the need for new predictive models to guide risk assessment on AR transmission and spread in aquatic environments.

Spatially Explicit Wastewater Generation and Tracking (SEWAGE-TRACK) in the Middle East and North Africa region.

This study developed the SEWAGE-TRACK model for disaggregating lumped national wastewater generation estimates using population datasets and quantifying rural and urban wastewater generation and fate. The model allocates wastewater into riparian, coastal, and inland components and summarizes the fate of wastewater into productive (direct and indirect reuse) and unproductive components for 19 countries in the Middle East and North Africa (MENA) region. As per the national estimates, 18.4 km3 of municipal wastewater generated in 2015, was disaggregated over the MENA region. Results from this study revealed urban and rural areas to contribute to 79 % and 21 % of municipal wastewater generation respectively. Within the rural context, inland areas generated 61 % of the total wastewater. The riparian and coastal regions produced 27 % and 12 %, respectively. Within the urban settings, riparian areas produced 48 %, while inland and coastal regions generated 34 % and 18 % of the total wastewater, respectively. Results indicate that 46 % of the wastewater is productively used (direct reuse and indirect use), while 54 % is lost unproductively. Of the total wastewater generated, the most direct use was observed in the coastal areas (7 %), the most indirect reuse in the riparian regions (31 %), and the most unproductive losses in inland areas (27 %). The potential of unproductive wastewater as a non-conventional freshwater source was also analyzed. Our results indicate that wastewater is an excellent alternative water source and has high potential to reduce pressure on non-renewable sources for some countries in the MENA region. The motivation of this study is to disaggregate wastewater generation and track wastewater fate using a simple but robust approach that is portable, scalable and repeatable. Similar analysis can be done for other regions to produce information on disaggregated wastewater and its fate. Such information is highly critical for efficient wastewater resource management.

A review on occurrence of emerging pollutants in waters of the MENA region.

Little is known about the occurrence of emerging pollutants (EPs) in waters in the Middle East and North Africa (MENA) region despite the extensive use of low-quality water there. Available data dealing with the sources, occurrence and removal of EPs within the MENA region in different categories of water is collected, presented and analyzed in this literature review. According to the collected database, the occurrence and removal efficiency of EPs in the water matrix in the MENA region is available, respectively, for 13 and six countries of the 18 in total; no available data is registered for the rest. Altogether, 290 EPs have been observed in different water matrices across the MENA countries, stemming mainly from industrial effluents, agricultural practices, and discharge or reuse of treated wastewater (TWW). Pharmaceutical compounds figure among the most frequently reported compounds in wastewater, TWW, surface water, and drinking water. Nevertheless, pesticides are the most frequently detected pollutants in groundwater. Worryingly, 57 cases of EPs have been reported in different fresh and drinking waters, exceeding World Health Organization (WHO) and European Commission (EC) thresholds. Overall, pharmaceuticals, organic compounds, and pesticides are the most concerning EP groups. The review revealed the ineffectiveness of treatment processes used in the region to remove EPs. Negative removals of some EPs such as carbamazepine, erythromycin, and sulfamethoxazole were recorded, suggesting their possible accumulation or release during treatment. This underlines the need to set in place and strengthen control measures, treatment procedures, standards, and policies for such pollutants in the region.

Innovative Research Approaches to Cope with Water Security in Africa.

To achieve a water-secure world, water management should be approached from a multidimensional and integrative perspective, addressing the water-related issues of health, household supply, economics, the environment, and resilience to water-related and climate change hazards. Although water security has significantly improved since 2000 in Africa, there are still vast inequalities in access to water suitable in terms of quantity and quality, especially in rural areas. To achieve water-related sustainable development of African economies, a broad scope of innovative technological and management solutions is required, involving governments, research institutions, private sector parties, and civil society. This special series, composed of 8 papers, illustrates a selection of the most relevant results achieved by the 7 research projects selected and financed by the European Union under 2 dedicated Horizon 2020 calls in 2015: Water-5b-2015 "A coordination platform" and Water-5c-2015 "Development of water supply and sanitation technology, systems and tools, and/or methodologies." The innovations presented in this special series include both technological advancements and w'ater management approaches, given that the development of water-related technologies in developing countries needs to be integrated into water management strategies and economic instruments. This special series aims to help policy makers take informed decisions on how to implement innovative approaches to increase water security in African countries. Integr Environ Assess Manag 2020;16:853-855. © 2020 The Authors. Integrated Environmental Assessment and Management published by Wiley Periodicals LLC on behalf of Society of Environmental Toxicology & Chemistry (SETAC).