RESUMO
SUMMARY: BLAST programs often run on large SMP machines where multiple threads can work simultaneously and there is enough memory to cache the databases between program runs. A group of programs is described which allows comparable performance to be achieved with a Beowulf configuration in which no node has enough memory to cache a database but the cluster as an aggregate does. To achieve this result, databases are split into equal sized pieces and stored locally on each node. Each query is run on all nodes in parallel and the resultant BLAST output files from all nodes merged to yield the final output. AVAILABILITY: Source code is available from ftp://saf.bio.caltech.edu/
Assuntos
Sistemas de Gerenciamento de Base de Dados , Bases de Dados de Proteínas , Armazenamento e Recuperação da Informação/métodos , Proteínas/química , Alinhamento de Sequência/métodos , Análise de Sequência de Proteína/métodos , Software , Sequência de Aminoácidos , Metodologias Computacionais , Internet , Dados de Sequência MolecularRESUMO
Drosophila melanogaster normally have six thoracic legs and no abdominal legs. However, one or two legs often appear in the first abdominal segment ofbithoraxoid mutants. The extent to which these extra legs develop is determined both by thecis-regulatory action ofbithoraxoid lesions onUltrabithorax and by the number of copies of the adjacent homeotic geneabdominal-A. Thebithoraxoid region does notcis-regulateabdominal-A.
