Tandem Protocol for the Synthesis of Pyrano[3,2-c]quinolone Derivatives Using Taurine as a Green Bio-Organic Catalyst in Aqueous Medium.

A series of pyrano[3,2-c]quinolone derivatives has been synthesized in the presence of taurine (2-aminoethanesulfonic acid) as a green bio-organic catalyst and water as the solvent. The target compounds were synthesized through the three-component reaction between aldehydes, malononitrile/ethylcyanoacetate, and 4-hydroxy-1-methyl-2(1H)-quinolone. The advantages of this protocol are excellent yields of products, short reaction times, cost efficiency, atom economy, and a simple work-up procedure with no need for extra purification techniques. Moreover, the catalyst can be easily recovered and reused for up to three cycles without losing any significant activity.

Surgical Management and Prosthetic Rehabilitation of Dentigerous Cyst Associated with Impacted Mandibular Canine: A Case Report.

The most frequent odontogenic developing cyst linked with an impacted tooth is the dentigerous cyst. They are normally asymptomatic and are identified during routine radiography tests to see if a tooth is missing from the arch. This case report is designed to demonstrate how an enucleated dentigerous cyst with impacted teeth led to the spontaneous recovery of a bone defect without the need for bone graft. The radiographic scan (OPG) 6 months after cystectomy revealed the creation of adequate bone for the insertion of the implants. As a result of this procedure, the patient's functional, physiologic, and psychological demands were addressed, and the cyst recurrence was avoided. Dental implants were the greatest choice for tooth replacement if significant bone regeneration could be achieved.