[Quantitative susceptibility mapping in assessment of inflammation and neurodegeneration in multiple sclerosis]. / Kolichestvennoe kartirovanie vospriimchivosti v otsenke vospalitel'nogo i neirodegenerativnogo protsessov pri rasseyannom skleroze.

Quantitative susceptibility mapping (QSM) is a relatively new MRI technique that may potentially help estimate iron concentrations in the brain. It plays a big role in diagnosis of many pathological processes, including multiple sclerosis (MS). Iron metabolism in the brain is a complex and not fully understood process. It is known that the content of iron in the brain increases with age; in addition, its accumulation is often observed in many neurodegenerative diseases, including MS foci, and its amount changes over time. In this regard, the values of magnetic susceptibility obtained using QSM can potentially become a convenient biomarker that reflects the latent activity and progression of MS, which, in turn, can influence the choice of therapy and the tactics of treating patients.