Determining pre-procedure fasting alert time using procedural and scheduling data.

Before a medical procedure requiring anesthesia, patients are required to not eat or drink non-clear fluids for 6 h and not drink clear fluids for 2 h. Fasting durations in standard practice far exceed these minimum thresholds due to uncertainties in procedure start time. The aim of this retrospective, observational study was to compare fasting durations arising from standard practice with different approaches for calculating the timepoint at which patients are instructed to stop eating and drinking. Scheduling data for procedures performed in the cardiac catheterization laboratory of an academic hospital in Canada (January 2020 to April 2022) were used. Four approaches utilizing machine learning (ML) and simulation were used to predict procedure start times and calculate when patients should be instructed to start fasting. Median fasting duration for standard practice was 10.08 h (IQR 3.5) for both food and clear fluids intake. The best performing alternative approach, using tree-based ML models to predict procedure start time, reduced median fasting from food/non-clear fluids to 7.7 h (IQR 2) and clear liquids fasting to 3.7 h (IQR 2.4). 97.3% met the minimum fasting duration requirements (95% CI 96.9% to 97.6%). Further studies are required to determine the effectiveness of operationalizing this approach as an automated fasting alert system.

Design Specifications for an Automated System to Deliver Instructions About Preprocedure Fasting.

PURPOSE: Many patients undergoing surgical and other medical procedures requiring sedation or anesthesia receive standardized "no eating or drinking after midnight" instructions. This "standardized" instruction does not change regardless of potential alterations in scheduling that result in significant delays in procedure start times. As a result, the duration of preprocedure fasting often far exceeds recommended requirements. A technological solution that automates the delivery of preprocedure fasting instructions to patients would likely improve the patient experience. The purpose of this study was to determine design specifications for the delivery of notifications to patients as part of an automated system. DESIGN: A qualitative study was conducted with 14 adult participants using the persona-scenario method. METHODS: Participants worked in groups to create realistic but fictitious personas and scenarios that described how individuals like themselves would interact with an automated preprocedure fasting instruction system. Data generated through the development of the scenarios were analyzed to first identify important themes, which were then interpreted into design specifications. FINDINGS: Seven women and seven men, aged 25 to 75, developed 9 persona-scenarios, which captured outpatient and inpatient preprocedure fasting experiences, as well as perspectives of individuals who were not comfortable with technology, or those for which English was not the primary spoken language. Most scenarios described preprocedure fasting instructions delivered by an automated bidirectional short message service system. Two major themes were identified as patient priorities, including: (1) enhancing communication between patients and healthcare providers; and (2) the importance of using simple technology so that a greater number of patients with varying degrees of comfort and capabilities would be able to use the system confidently. A corresponding set of proposed design specifications was devised. CONCLUSIONS: The results of this study provide actionable ways to operationalize patient-centered ideas in the design of an automated preprocedure fasting instruction system.

A mathematical model for antimalarial drug resistance.

We formulate and analyze a mathematical model for malaria with treatment and the well-known three levels of resistance in humans. The model incorporates both sensitive and resistant strains of the parasites. Analytical results reveal that the model exhibits the phenomenon of backward bifurcation (co-existence of a stable disease-free equilibrium with a stable endemic equilibrium), an epidemiological situation where although necessary, having the basic reproduction number less than unity, it is not sufficient for disease elimination. Through quantitative analysis, we show the effects of varying treatment levels in a high transmission area with different levels of resistance. Increasing treatment has limited benefits in a population with resistant strains, especially in high transmission settings. Thus, in a cost-benefit analysis, the rate of treatment and percentage to be treated become difficult questions to address.

Emergency preparedness volunteer training program.

The Vermont Department of Health (VDH) does not have sufficient personnel to fully staff a mass prophylaxis or vaccination clinic in response to a natural or man-made disease outbreak. Therefore, the VDH developed an emergency preparedness volunteer training program with three primary goals: to include both background information about public health and emergency preparedness and a hands-on training for clinic volunteers; to be adaptable for both community and healthcare professional volunteers; and to examine local emergencies and the VDH public health response to these events. Major components of the training program include basic public health goals and capacities; an introduction to emergency preparedness; a role-playing exercise using Job Action Sheets to simulate "just-in-time" training; and guidance for personal and family preparedness. The VDH has experienced difficulty finding and recruiting volunteers. To increase the potential volunteer pool, it will be implementing a multifaceted training program (on-line, through the mail, in person) to most effectively engage volunteers with varying interests and learning styles. The VDH must also develop a system to maintain regular contact with volunteers and clarify regulations regarding their scope of practice and liability.

The nonconsciousness of self-consciousness.

Five studies demonstrated that private self-consciousness is associated with nonconscious, automatic behaviors. In 2 studies, high but not low self-conscious individuals walked more slowly following exposure to an implicit elderly prime. In a 3rd study, high but not low self-conscious individuals showed improved performance following exposure to a subliminal success prime relative to a subliminal failure prime. In a 4th study, subliminal exposure to an angry prime was shown to increase blood pressure relative to a relax prime. In a final study, the latter effect was shown to be true only for high self-conscious individuals and only for subliminal presentations. Results are discussed in terms of their implications for understanding a variety of effects associated with self-consciousness and self-awareness.

Improving the effectiveness of continuous closed chest compressions: an exploratory study.

UNLABELLED: This study was carried out to establish the length of time over which an individual can maintain effective chest compressions and the most effective pattern of rest and handover among a team. The continuing effectiveness of chest compressions was compared between groups of 2 or 3 rescuers performing chest compressions for 1, 2 or 3 min during scenarios lasting 18 min. Evaluation of the effectiveness of compressions was achieved using a computerised resuscitation manikin (Laerdal/Skillmeter) on a hospital trolley. Twenty-one volunteers competent in basic life support participated. The results were analysed using one-way analysis of variance and Dunnett's contrast of the various scenarios. The results demonstrated that a three person team delivering 1 min periods of chest compressions in rotation is significantly better than other sequences at 5 min and beyond (P<0.0001). At 18 min 91.5% of all chest compressions delivered by this three person team were greater than 70% effective. There was no significant difference between the first and final set of chest compressions. CONCLUSION: Continuous chest compressions performed for 1 min, preferably by three rescuers in rotation, maintain a high level of effectiveness. Longer periods of chest compressions should be discouraged.