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J Agric Food Chem ; 65(38): 8459-8465, 2017 Sep 27.
Artigo em Inglês | MEDLINE | ID: mdl-28892386

RESUMO

MZHG0JG corn will offer growers the flexibility to alternate between herbicides with two different modes of action in their weed-management programs, helping to mitigate and manage the evolution of herbicide resistance in weed populations. The proteins conferring herbicide tolerence in MZHG0JG corn, double-mutated 5-enol pyruvylshikimate-3-phosphate synthase protein (mEPSPS) and phosphinothricin acetyltransferase (PAT), as well as the MZHG0JG corn event, have been assessed by regulatory authorities globally and have been determined to be safe for humans, animals, and the environment. In addition to the safety data available for these proteins, further studies were conducted on MZHG0JG corn to assess levels of mEPSPS as compared to previously registered genetically modified (GM) corn. The results support the conclusion of no impact on toxicological safety or nutritional composition.


Assuntos
3-Fosfoshikimato 1-Carboxiviniltransferase/genética , Acetiltransferases/genética , Proteínas de Bactérias/genética , Plantas Geneticamente Modificadas/genética , Zea mays/genética , 3-Fosfoshikimato 1-Carboxiviniltransferase/metabolismo , Acetiltransferases/metabolismo , Agrobacterium tumefaciens/enzimologia , Proteínas de Bactérias/metabolismo , Análise de Perigos e Pontos Críticos de Controle , Resistência a Herbicidas , Herbicidas/farmacologia , Mutação , Valor Nutritivo , Plantas Geneticamente Modificadas/efeitos adversos , Plantas Geneticamente Modificadas/efeitos dos fármacos , Plantas Geneticamente Modificadas/metabolismo , Streptomyces/enzimologia , Zea mays/efeitos adversos , Zea mays/efeitos dos fármacos , Zea mays/metabolismo
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