Characterization of xylitol or citric acid:choline chloride:water mixtures: Structure, thermophysical properties, and quercetin solubility.

The industrial implementation of new eco-friendly solvents has highlighted the need to analyse both the structures and thermophysical properties of these solvents. Here, two deep eutectic solvents (DESs) used in the agro-food field were studied: xylitol:choline chloride:water (1:2:3 M ratio), XoCH, and citric acid:choline chloride:water (1:1:6 M ratio), CiCH. The H-bond network between the components of each DES was evaluated and the diffusion coefficients at 298.15 K were calculated using NMR spectroscopy. In addition, seven thermophysical properties were determined from 278.15 to 338.15 K. Also, the solubility of quercetin in water and in the two eutectic mixtures was measured and the interactions between components were studied. NMR experiments revealed the presence of water within the supramolecular structure of XoCH, but CiCH is a "DES-in-water" solution. Based on the results, XoCH is the most compact mixture. Finally, quercetin was remarkably more soluble in the studied DESs than in pure water.

Toxocariasis: a propósito de un caso; revisión de la literatura / Toxocariasis: apropos of a case; review of the literature

La toxocariasis humana es una enfermedad producida por la infestación de huésped por larvas de Toxocara canis. Las formas clínicas son variadas y dependen del órgano afectado. Se han descrito la forma de larva migrans visceral, toxocariasis ocular, toxocariasis oculta y una forma asintomática. El diagnóstico se basa en las pruebas serológicas, siendo el Elisa la más confiable. El tratamiento es controversial y se indica dependiendo de la severidad del cuadro ya que no existe una droga totalmente efectiva. El objetivo es presentar la evolución de un caso clínico de larva migrans visceral durante un año quien mantiene eosinofilia persistente con exacerbaciones clínicas a pesar del tratamiento con albendazol, probablemente causadas por reinfección ya que se mantiene en el mismo medio ambiente. Se enfatizan las medidas de prevención para evitar la infección y reinfección