Impact of the International Nosocomial Infection Control Consortium (INICC)'s Multidimensional Approach on Rates of Central Line-Associated Bloodstream Infection in 14 Intensive Care Units in 11 Hospitals of 5 Cities in Argentina.

OBJECTIVE To analyze the impact of the International Nosocomial Infection Control Consortium (INICC) Multidimensional Approach (IMA) and the INICC Surveillance Online System (ISOS) on central line-associated bloodstream infection (CLABSI) rates in 14 intensive care units (ICUs) in Argentina from January 2014 to April 2017. DESIGN This prospective, pre-post surveillance study of 3,940 ICU patients was conducted in 11 hospitals in 5 cities in Argentina. During our baseline evaluation, we performed outcome and process surveillance of CLABSI applying Centers for Disease Control and Prevention/National Health Safety Network (CDC/NHSN) definitions. During the intervention, we implemented the IMA through ISOS: (1) a bundle of infection prevention practice interventions, (2) education, (3) outcome surveillance, (4) process surveillance, (5) feedback on CLABSI rates and consequences, and (6) performance feedback of process surveillance. Bivariate and multivariate regression analyses were performed using a logistic regression model to estimate the effect of the intervention on the CLABSI rate. RESULTS During the baseline period, 5,118 CL days and 49 CLABSIs were recorded, for a rate of 9.6 CLABSIs per 1,000 central-line (CL) days. During the intervention, 15,659 CL days and 68 CLABSIs were recorded, for a rate of 4.1 CLABSIs per 1,000 CL days. The CLABSI rate was reduced by 57% (incidence density rate: 0.43; 95% confidence interval, 0.34-0.6; P<.001). CONCLUSIONS Implementing IMA through ISOS was associated with a significant reduction in the CLABSI rate in ICUs in Argentina. Infect Control Hosp Epidemiol 2018;39:445-451.

Impact of the International Nosocomial Infection Control Consortium's multidimensional approach on rates of ventilator-associated pneumonia in 14 intensive care units in 11 hospitals of 5 cities within Argentina.

BACKGROUND: To analyze the impact of the International Nosocomial Infection Control Consortium (INICC) multidimensional approach (IMA) on ventilator-associated pneumonia (VAP) rates in 11 hospitals within 5 cities of Argentina from January 2014-April 2017. METHODS: A multicenter, prospective, before-after surveillance study was conducted through the use of International Nosocomial Infection Control Consortium Surveillance Online System. During baseline, we performed outcome surveillance of VAP applying the definitions of the Centers for Disease Control andPrevention's National Healthcare Safety Network. During intervention, we implemented the IMA, which included a bundle of infection prevention practice interventions, education, outcome surveillance, process surveillance, feedback on VAP rates and consequences, and performance feedback of process surveillance. Bivariate and multivariate regression analyses were performed using a logistic regression model to estimate the effect of the intervention. RESULTS: We recorded 3,940 patients admitted to 14 intensive care units. At baseline, there were 19.9 VAPs per 1,000 mechanical ventilator (MV)-days-with 2,920 MV-days and 58 VAPs, which was reduced during intervention to 9.4 VAPs per 1,000 MV-days-with 9,261 MV-days and 103 VAPs. This accounted for a 52% rate reduction (incidence density rate, 0.48; 95% confidence interval, 0.3-0.7; P .001). CONCLUSIONS: Implementing the IMA was associated with significant reductions in VAP rates in intensive care units within Argentina.

Infecciones asociadas a catéteres en terapia intensiva del Hospital Privado del Sur de Bahía Blanca / Catheter-associated infections at the intensive care unit of the hospital Privado del Sur, Bahía Blanca

Introducción: El uso de accesos venosos centrales (AVC) es útil para tratamiento y monitoreo hemodinámico del paciente. Sin embargo, su implementación no está exenta de complicaciones, siendo el principal problema las complicaciones infecciosas asociadas al catéter. Materiales y Métodos. En el servicio de Terapia Intensiva del Hospital Privado del Sur (HPS), se realizó un estudio descriptivo, retrospectivo acerca de la incidencia de infecciones asociadas a catéter (IAC) en la población de pacientes adultos internados durante el período 2006 ­ 2011; y se midió el impacto del paquete de medidas propuestas por el Comité de Control de Infecciones diseñadas para reducir la incidencia de las IAC. Resultados: La tasa de uso de AVC fue de 73,76% y la tasa total de IAC fue de 7,16/1000 día catéter. Se observa un descenso de IAC, de 15/1000 día catéter en 2006 a 7,8 en el año 2011. De la flora predominante 53,8% fueron bacilos Gram negativos, cocos Gram positivo el 46,2% restante, y entre ellos sólo 5,13% fue por Staphylococcus aureus meticilinorresistente. Conclusiones: Nuestros datos muestran un importante descenso en las tasas de infección desde la implementación del Programa de Control de Infecciones diseñado por el Comité de Control de Infecciones del HPS, en 2008.

Introduction: The use of central venous accesses (CVA) is useful for the hemodynamic monitoring and treatment of patients. However, its implementation may present some complications being catheter-associated infections the major problem. Materials and Methods: In the Intensive Care Unit of the Hospital Privado del Sur (HPS), we conducted a descriptive study on the incidence of catheter-associated infections (CAI) in an adult patient population admitted during the period 2006-2011, and we measured the impact of the set of measures proposed by the Infection Control Committee designed to reduce the incidence of CAI. Results: The CVA prevalence rate was 73.76% and the overall rate was 7.16 CAI / 1000 catheter days. We observed a decrease in CAI, 15/1000 catheter days in 2006 to 7.8 in the year 2011. Predominant flora were Gram negative bacteria 53.8%, and Gram positive cocci the remaining 46.2%. Among them there was only 5.13% infections caused by methicillin-resistant Staphylococcus aureus. Conclusions: Our data show a significant decrease in infection rates since the implementation of the Infection Control Program designed by the Infection Control Committee of the HPS in 2008.